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Fused tricyclic mGluR1 antagonists for the treatment of neuropathic pain.
Bennett CE, Burnett DA, Greenlee WJ, Knutson CE, Korakas P, Li C, Tulshian D, Wu WL, Bertorelli R, Fredduzzi S, Grilli M, Lozza G, Reggiani A, Veltri A. Bennett CE, et al. Among authors: grilli m. Bioorg Med Chem Lett. 2012 Feb 15;22(4):1575-8. doi: 10.1016/j.bmcl.2011.12.131. Epub 2012 Jan 3. Bioorg Med Chem Lett. 2012. PMID: 22266036
Synthesis and SAR development of novel mGluR1 antagonists for the treatment of chronic pain.
Brumfield S, Korakas P, Silverman LS, Tulshian D, Matasi JJ, Qiang L, Bennett CE, Burnett DA, Greenlee WJ, Knutson CE, Wu WL, Sasikumar TK, Domalski M, Bertorelli R, Grilli M, Lozza G, Reggiani A, Li C. Brumfield S, et al. Among authors: grilli m. Bioorg Med Chem Lett. 2012 Dec 1;22(23):7223-6. doi: 10.1016/j.bmcl.2012.09.048. Epub 2012 Oct 2. Bioorg Med Chem Lett. 2012. PMID: 23084894
The antinociceptive and anxiolytic-like effects of the metabotropic glutamate receptor 5 (mGluR5) antagonists, MPEP and MTEP, and the mGluR1 antagonist, LY456236, in rodents: a comparison of efficacy and side-effect profiles.
Varty GB, Grilli M, Forlani A, Fredduzzi S, Grzelak ME, Guthrie DH, Hodgson RA, Lu SX, Nicolussi E, Pond AJ, Parker EM, Hunter JC, Higgins GA, Reggiani A, Bertorelli R. Varty GB, et al. Among authors: grilli m. Psychopharmacology (Berl). 2005 Apr;179(1):207-17. doi: 10.1007/s00213-005-2143-4. Epub 2005 Jan 29. Psychopharmacology (Berl). 2005. PMID: 15682298
347 results