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Sequential inactivation of rdxA (HP0954) and frxA (HP0642) nitroreductase genes causes moderate and high-level metronidazole resistance in Helicobacter pylori.
Jeong JY, Mukhopadhyay AK, Dailidiene D, Wang Y, Velapatiño B, Gilman RH, Parkinson AJ, Nair GB, Wong BC, Lam SK, Mistry R, Segal I, Yuan Y, Gao H, Alarcon T, Brea ML, Ito Y, Kersulyte D, Lee HK, Gong Y, Goodwin A, Hoffman PS, Berg DE. Jeong JY, et al. Among authors: goodwin a. J Bacteriol. 2000 Sep;182(18):5082-90. doi: 10.1128/JB.182.18.5082-5090.2000. J Bacteriol. 2000. PMID: 10960091 Free PMC article.
Insertion of mini-IS605 and deletion of adjacent sequences in the nitroreductase (rdxA) gene cause metronidazole resistance in Helicobacter pylori NCTC11637.
Debets-Ossenkopp YJ, Pot RG, van Westerloo DJ, Goodwin A, Vandenbroucke-Grauls CM, Berg DE, Hoffman PS, Kusters JG. Debets-Ossenkopp YJ, et al. Among authors: goodwin a. Antimicrob Agents Chemother. 1999 Nov;43(11):2657-62. doi: 10.1128/AAC.43.11.2657. Antimicrob Agents Chemother. 1999. PMID: 10543743 Free PMC article.
912 results