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A proprotein convertase subtilisin/kexin type 9 neutralizing antibody reduces serum cholesterol in mice and nonhuman primates.
Chan JC, Piper DE, Cao Q, Liu D, King C, Wang W, Tang J, Liu Q, Higbee J, Xia Z, Di Y, Shetterly S, Arimura Z, Salomonis H, Romanow WG, Thibault ST, Zhang R, Cao P, Yang XP, Yu T, Lu M, Retter MW, Kwon G, Henne K, Pan O, Tsai MM, Fuchslocher B, Yang E, Zhou L, Lee KJ, Daris M, Sheng J, Wang Y, Shen WD, Yeh WC, Emery M, Walker NP, Shan B, Schwarz M, Jackson SM. Chan JC, et al. Among authors: zhang r. Proc Natl Acad Sci U S A. 2009 Jun 16;106(24):9820-5. doi: 10.1073/pnas.0903849106. Epub 2009 May 14. Proc Natl Acad Sci U S A. 2009. PMID: 19443683 Free PMC article.
The high-resolution crystal structure of human LCAT.
Piper DE, Romanow WG, Gunawardane RN, Fordstrom P, Masterman S, Pan O, Thibault ST, Zhang R, Meininger D, Schwarz M, Wang Z, King C, Zhou M, Walker NP. Piper DE, et al. Among authors: zhang r. J Lipid Res. 2015 Sep;56(9):1711-9. doi: 10.1194/jlr.M059873. Epub 2015 Jul 20. J Lipid Res. 2015. PMID: 26195816 Free PMC article.
Agonistic Human Antibodies Binding to Lecithin-Cholesterol Acyltransferase Modulate High Density Lipoprotein Metabolism.
Gunawardane RN, Fordstrom P, Piper DE, Masterman S, Siu S, Liu D, Brown M, Lu M, Tang J, Zhang R, Cheng J, Gates A, Meininger D, Chan J, Carlson T, Walker N, Schwarz M, Delaney J, Zhou M. Gunawardane RN, et al. Among authors: zhang r. J Biol Chem. 2016 Feb 5;291(6):2799-811. doi: 10.1074/jbc.M115.672790. Epub 2015 Dec 7. J Biol Chem. 2016. PMID: 26644477 Free PMC article.
Generation of novel long-acting globular adiponectin molecules.
Ge H, Xiong Y, Lemon B, Lee KJ, Tang J, Wang P, Weiszmann J, Hawkins N, Laudemann J, Min X, Penny D, Wolfe T, Liu Q, Zhang R, Yeh WC, Shen W, Lindberg R, Wang Z, Sheng J, Li Y. Ge H, et al. Among authors: zhang r. J Mol Biol. 2010 May 28;399(1):113-9. doi: 10.1016/j.jmb.2010.03.062. Epub 2010 Apr 9. J Mol Biol. 2010. PMID: 20382165
Recombinant human lecithin-cholesterol acyltransferase Fc fusion: analysis of N- and O-linked glycans and identification and elimination of a xylose-based O-linked tetrasaccharide core in the linker region.
Spahr C, Kim JJ, Deng S, Kodama P, Xia Z, Tang J, Zhang R, Siu S, Nuanmanee N, Estes B, Stevens J, Zhou M, Lu HS. Spahr C, et al. Among authors: zhang r. Protein Sci. 2013 Dec;22(12):1739-53. doi: 10.1002/pro.2373. Protein Sci. 2013. PMID: 24115046 Free PMC article.
Observed Effects on Very Early Pregnancy Linked to Ambient PM2.5 Exposure in China among Women Undergoing In Vitro Fertilization-Embryo Transfer.
Lan C, Guan Y, Luo H, Ma X, Yang Y, Bao H, Hao C, He X, Zhang H, Gao N, Lin W, Ren M, Wu T, Wang C, Ni X, Shen C, Zhang J, Ma J, Zhang R, Bi Y, Zhuang L, Miao R, Song Z, An T, Liu Z, Pan B, Fang M, Liu J, Bai Z, Meng F, Chen Y, Lu X, Guo Y, Cao Y, Lu Q, Wang B. Lan C, et al. Among authors: zhang r. Environ Health (Wash). 2024 Oct 21;2(12):918-928. doi: 10.1021/envhealth.4c00107. eCollection 2024 Dec 20. Environ Health (Wash). 2024. PMID: 39722841 Free PMC article.
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