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Discovery of tetrasubstituted imidazolines as potent and selective neuropeptide Y Y5 receptor antagonists: reduced human ether-a-go-go related gene potassium channel binding affinity and potent antiobesity effect.
Sato N, Ando M, Ishikawa S, Jitsuoka M, Nagai K, Takahashi H, Sakuraba A, Tsuge H, Kitazawa H, Iwaasa H, Mashiko S, Gomori A, Moriya R, Fujino N, Ohe T, Ishihara A, Kanatani A, Fukami T. Sato N, et al. Among authors: nagai k. J Med Chem. 2009 May 28;52(10):3385-96. doi: 10.1021/jm900110t. J Med Chem. 2009. PMID: 19459652
Discovery of novel spiro-piperidine derivatives as highly potent and selective melanin-concentrating hormone 1 receptor antagonists.
Suzuki T, Moriya M, Sakamoto T, Suga T, Kishino H, Takahashi H, Ishikawa M, Nagai K, Imai Y, Sekino E, Ito M, Iwaasa H, Ishihara A, Tokita S, Kanatani A, Sato N, Fukami T. Suzuki T, et al. Among authors: nagai k. Bioorg Med Chem Lett. 2009 Jun 1;19(11):3072-7. doi: 10.1016/j.bmcl.2009.04.016. Epub 2009 Apr 9. Bioorg Med Chem Lett. 2009. PMID: 19403308
Discovery of pyridone-containing imidazolines as potent and selective inhibitors of neuropeptide Y Y5 receptor.
Ando M, Sato N, Nagase T, Nagai K, Ishikawa S, Takahashi H, Ohtake N, Ito J, Hirayama M, Mitobe Y, Iwaasa H, Gomori A, Matsushita H, Tadano K, Fujino N, Tanaka S, Ohe T, Ishihara A, Kanatani A, Fukami T. Ando M, et al. Among authors: nagai k. Bioorg Med Chem. 2009 Aug 15;17(16):6106-22. doi: 10.1016/j.bmc.2009.05.069. Epub 2009 Jun 2. Bioorg Med Chem. 2009. PMID: 19616955
Verification in an animal study of the appropriate settings for a novel radiofrequency generator in radiofrequency ablation therapy for residual intraductal lesions after endoscopic papillectomy (with video).
Yamamoto K, Itoi T, Sofuni A, Tsuchiya T, Tanaka R, Tonozuka R, Nagai K, Matsunami Y, Kojima H, Minami H, Hirakawa N, Asano K, Mukai S. Yamamoto K, et al. Among authors: nagai k. Dig Endosc. 2025 Jan 20. doi: 10.1111/den.14986. Online ahead of print. Dig Endosc. 2025. PMID: 39833995
Role and prognostic value of growth differentiation factor 15 in patient of heart failure with preserved ejection fraction: insights from the PURSUIT-HFpEF registry.
Sakamoto D, Matsuoka Y, Nakatani D, Okada K, Sunaga A, Kida H, Sato T, Kitamura T, Tamaki S, Seo M, Yano M, Hayashi T, Nakagawa A, Nakagawa Y, Yasumura Y, Yamada T, Hikoso S, Sotomi Y, Sakata Y; OCVC-Heart Failure Investigators. Sakamoto D, et al. Open Heart. 2025 Jan 19;12(1):e003008. doi: 10.1136/openhrt-2024-003008. Open Heart. 2025. PMID: 39832941 Free article.
Metachronous Pancreatic Cancer with Pancreaticobiliary Maljunction Diagnosed Five Years after Cholecystectomy for Gallbladder Cancer, in Which Follow-up Imaging was Possible Until the Onset of Cancer: A Case Report and Review of the Literature.
Miyazawa M, Yanagi M, Chiba T, Nagai K, Kido H, Sugimoto S, Nishitani M, Orita N, Takata N, Hayashi T, Seki A, Nakagawa H, Nio K, Terashima T, Iida N, Yamada S, Takatori H, Shimakami T, Mizukoshi E, Honda M, Yamashita T. Miyazawa M, et al. Among authors: nagai k. Intern Med. 2025 Jan 15. doi: 10.2169/internalmedicine.4581-24. Online ahead of print. Intern Med. 2025. PMID: 39814388 Free article.
Novel desensitization therapy of mesalamine intolerance in patients with ulcerative colitis.
Kinoshita K, Sawaguchi S, Toyoshima K, Yoshida S, Yamamura T, Nagai K, Tanaka I, Hatanaka K, Yamamoto Y, Naruse H, Katsurada T, Sakamoto N. Kinoshita K, et al. Among authors: nagai k. Gastroenterol Hepatol. 2025 Jan 9:502347. doi: 10.1016/j.gastrohep.2025.502347. Online ahead of print. Gastroenterol Hepatol. 2025. PMID: 39798847 Free article. English, Spanish.
3,900 results