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Discovery of tetrasubstituted imidazolines as potent and selective neuropeptide Y Y5 receptor antagonists: reduced human ether-a-go-go related gene potassium channel binding affinity and potent antiobesity effect.
Sato N, Ando M, Ishikawa S, Jitsuoka M, Nagai K, Takahashi H, Sakuraba A, Tsuge H, Kitazawa H, Iwaasa H, Mashiko S, Gomori A, Moriya R, Fujino N, Ohe T, Ishihara A, Kanatani A, Fukami T. Sato N, et al. Among authors: tsuge h. J Med Chem. 2009 May 28;52(10):3385-96. doi: 10.1021/jm900110t. J Med Chem. 2009. PMID: 19459652
Novel orally active NPY Y5 receptor antagonists: Synthesis and structure-activity relationship of spiroindoline class compounds.
Sakamoto T, Moriya M, Tsuge H, Takahashi T, Haga Y, Nonoshita K, Okamoto O, Takahashi H, Sakuraba A, Hirohashi T, Shibata T, Kanno T, Ito J, Iwaasa H, Gomori A, Ishihara A, Fukuroda T, Kanatani A, Fukami T. Sakamoto T, et al. Among authors: tsuge h. Bioorg Med Chem. 2009 Jul 15;17(14):5015-26. doi: 10.1016/j.bmc.2009.05.064. Epub 2009 Jun 2. Bioorg Med Chem. 2009. PMID: 19525116
Structural Elucidation and Antiviral Activity of Covalent Cathepsin L Inhibitors.
Falke S, Lieske J, Herrmann A, Loboda J, Karničar K, Günther S, Reinke PYA, Ewert W, Usenik A, Lindič N, Sekirnik A, Dretnik K, Tsuge H, Turk V, Chapman HN, Hinrichs W, Ebert G, Turk D, Meents A. Falke S, et al. Among authors: tsuge h. J Med Chem. 2024 May 9;67(9):7048-7067. doi: 10.1021/acs.jmedchem.3c02351. Epub 2024 Apr 17. J Med Chem. 2024. PMID: 38630165 Free PMC article.
Body mass index and lung cancer risk: Pooled analysis of 10 prospective cohort studies in Japan.
Kawai S, Lin Y, Tsuge H, Ito H, Matsuo K, Wada K, Nagata C, Narii N, Kitamura T, Utada M, Sakata R, Kimura T, Tamakoshi A, Sugawara Y, Tsuji I, Suzuki S, Sawada N, Tsugane S, Mizoue T, Oze I, Abe SK, Inoue M; Research Group for the Development and Evaluation of Cancer Prevention Strategies in Japan. Kawai S, et al. Among authors: tsuge h. Cancer Sci. 2024 Apr;115(4):1346-1359. doi: 10.1111/cas.16093. Epub 2024 Feb 4. Cancer Sci. 2024. PMID: 38310695 Free PMC article.
202 results