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Elevation of plasma beta-amyloid level by glucose loading in Alzheimer mouse models.
Takeda S, Sato N, Uchio-Yamada K, Sawada K, Kunieda T, Takeuchi D, Kurinami H, Shinohara M, Rakugi H, Morishita R. Takeda S, et al. Among authors: kurinami h. Biochem Biophys Res Commun. 2009 Jul 24;385(2):193-7. doi: 10.1016/j.bbrc.2009.05.037. Epub 2009 May 18. Biochem Biophys Res Commun. 2009. PMID: 19450564
Diabetes-accelerated memory dysfunction via cerebrovascular inflammation and Abeta deposition in an Alzheimer mouse model with diabetes.
Takeda S, Sato N, Uchio-Yamada K, Sawada K, Kunieda T, Takeuchi D, Kurinami H, Shinohara M, Rakugi H, Morishita R. Takeda S, et al. Among authors: kurinami h. Proc Natl Acad Sci U S A. 2010 Apr 13;107(15):7036-41. doi: 10.1073/pnas.1000645107. Epub 2010 Mar 15. Proc Natl Acad Sci U S A. 2010. PMID: 20231468 Free PMC article.
Development of new screening system for Alzheimer disease, in vitro Abeta sink assay, to identify the dissociation of soluble Abeta from fibrils.
Sato N, Okochi M, Taniyama Y, Kurinami H, Shimamura M, Takeuchi D, Hamada H, Fukumori A, Kiyosue K, Taguchi T, Tanaka T, Miyasaka M, Takeda M, Ogihara T, Morishita R. Sato N, et al. Among authors: kurinami h. Neurobiol Dis. 2006 Jun;22(3):487-95. doi: 10.1016/j.nbd.2005.12.010. Epub 2006 Feb 20. Neurobiol Dis. 2006. PMID: 16488151
Reduction of brain beta-amyloid (Abeta) by fluvastatin, a hydroxymethylglutaryl-CoA reductase inhibitor, through increase in degradation of amyloid precursor protein C-terminal fragments (APP-CTFs) and Abeta clearance.
Shinohara M, Sato N, Kurinami H, Takeuchi D, Takeda S, Shimamura M, Yamashita T, Uchiyama Y, Rakugi H, Morishita R. Shinohara M, et al. Among authors: kurinami h. J Biol Chem. 2010 Jul 16;285(29):22091-102. doi: 10.1074/jbc.M110.102277. Epub 2010 May 14. J Biol Chem. 2010. PMID: 20472556 Free PMC article.
36 results