DeGrado WF - Search Results

1

Discovery of spiro-piperidine inhibitors and their modulation of the dynamics of the M2 proton channel from influenza A virus.

Wang J, Cady SD, Balannik V, Pinto LH, DeGrado WF, Hong M. Wang J, et al. Among authors: degrado wf. J Am Chem Soc. 2009 Jun 17;131(23):8066-76. doi: 10.1021/ja900063s. J Am Chem Soc. 2009. PMID: 19469531 Free PMC article.

2

A functionally defined model for the M2 proton channel of influenza A virus suggests a mechanism for its ion selectivity.

Pinto LH, Dieckmann GR, Gandhi CS, Papworth CG, Braman J, Shaughnessy MA, Lear JD, Lamb RA, DeGrado WF. Pinto LH, et al. Among authors: degrado wf. Proc Natl Acad Sci U S A. 1997 Oct 14;94(21):11301-6. doi: 10.1073/pnas.94.21.11301. Proc Natl Acad Sci U S A. 1997. PMID: 9326604 Free PMC article.

3

Cu(II) inhibition of the proton translocation machinery of the influenza A virus M2 protein.

Gandhi CS, Shuck K, Lear JD, Dieckmann GR, DeGrado WF, Lamb RA, Pinto LH. Gandhi CS, et al. Among authors: degrado wf. J Biol Chem. 1999 Feb 26;274(9):5474-82. doi: 10.1074/jbc.274.9.5474. J Biol Chem. 1999. PMID: 10026160 Free article.

4

pH-dependent tetramerization and amantadine binding of the transmembrane helix of M2 from the influenza A virus.

Salom D, Hill BR, Lear JD, DeGrado WF. Salom D, et al. Among authors: degrado wf. Biochemistry. 2000 Nov 21;39(46):14160-70. doi: 10.1021/bi001799u. Biochemistry. 2000. PMID: 11087364 Free PMC article.

5

De novo design of a monomeric helical beta-peptide stabilized by electrostatic interactions.

Cheng RP, DeGrado WF. Cheng RP, et al. Among authors: degrado wf. J Am Chem Soc. 2001 May 30;123(21):5162-3. doi: 10.1021/ja010438e. J Am Chem Soc. 2001. PMID: 11457373 No abstract available.

6

De novo design, synthesis, and characterization of antimicrobial beta-peptides.

Liu D, DeGrado WF. Liu D, et al. Among authors: degrado wf. J Am Chem Soc. 2001 Aug 8;123(31):7553-9. doi: 10.1021/ja0107475. J Am Chem Soc. 2001. PMID: 11480975

7

Temperature-dependent helix-coil transition of an alanine based peptide.

Huang CY, Klemke JW, Getahun Z, DeGrado WF, Gai F. Huang CY, et al. Among authors: degrado wf. J Am Chem Soc. 2001 Sep 26;123(38):9235-8. doi: 10.1021/ja0158814. J Am Chem Soc. 2001. PMID: 11562202

8

Time-resolved infrared study of the helix-coil transition using (13)C-labeled helical peptides.

Huang CY, Getahun Z, Wang T, DeGrado WF, Gai F. Huang CY, et al. Among authors: degrado wf. J Am Chem Soc. 2001 Dec 5;123(48):12111-2. doi: 10.1021/ja016631q. J Am Chem Soc. 2001. PMID: 11724630 No abstract available.

9

Template-constrained somatostatin analogues: a biphenyl linker induces a type-V' turn.

Cheng RP, Suich DJ, Cheng H, Roder H, DeGrado WF. Cheng RP, et al. Among authors: degrado wf. J Am Chem Soc. 2001 Dec 19;123(50):12710-1. doi: 10.1021/ja0116932. J Am Chem Soc. 2001. PMID: 11741449 No abstract available.

10

Long-range interactions stabilize the fold of a non-natural oligomer.

Cheng RP, DeGrado WF. Cheng RP, et al. Among authors: degrado wf. J Am Chem Soc. 2002 Oct 2;124(39):11564-5. doi: 10.1021/ja020728a. J Am Chem Soc. 2002. PMID: 12296699

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