Knauf JA - Search Results

1

Mutational profile of advanced primary and metastatic radioactive iodine-refractory thyroid cancers reveals distinct pathogenetic roles for BRAF, PIK3CA, and AKT1.

Ricarte-Filho JC, Ryder M, Chitale DA, Rivera M, Heguy A, Ladanyi M, Janakiraman M, Solit D, Knauf JA, Tuttle RM, Ghossein RA, Fagin JA. Ricarte-Filho JC, et al. Among authors: knauf ja. Cancer Res. 2009 Jun 1;69(11):4885-93. doi: 10.1158/0008-5472.CAN-09-0727. Cancer Res. 2009. PMID: 19487299 Free PMC article.

2

Identification of rapid turnover transcripts overexpressed in thyroid tumors and thyroid cancer cell lines: use of a targeted differential RNA display method to select for mRNA subsets.

Gonsky R, Knauf JA, Elisei R, Wang JW, Su S, Fagin JA. Gonsky R, et al. Among authors: knauf ja. Nucleic Acids Res. 1997 Oct 1;25(19):3823-31. doi: 10.1093/nar/25.19.3823. Nucleic Acids Res. 1997. PMID: 9380504 Free PMC article.

3

From amplification to gene in thyroid cancer: a high-resolution mapped bacterial-artificial-chromosome resource for cancer chromosome aberrations guides gene discovery after comparative genome hybridization.

Chen X, Knauf JA, Gonsky R, Wang M, Lai EH, Chissoe S, Fagin JA, Korenberg JR. Chen X, et al. Among authors: knauf ja. Am J Hum Genet. 1998 Aug;63(2):625-37. doi: 10.1086/301973. Am J Hum Genet. 1998. PMID: 9683604 Free PMC article.

4

Mechanisms of aneuploidy in thyroid cancer cell lines and tissues: evidence for mitotic checkpoint dysfunction without mutations in BUB1 and BUBR1.

Ouyang B, Knauf JA, Ain K, Nacev B, Fagin JA. Ouyang B, et al. Among authors: knauf ja. Clin Endocrinol (Oxf). 2002 Mar;56(3):341-50. doi: 10.1046/j.1365-2265.2002.01475.x. Clin Endocrinol (Oxf). 2002. PMID: 11940046

5

Isozyme-specific abnormalities of PKC in thyroid cancer: evidence for post-transcriptional changes in PKC epsilon.

Knauf JA, Ward LS, Nikiforov YE, Nikiforova M, Puxeddu E, Medvedovic M, Liron T, Mochly-Rosen D, Fagin JA. Knauf JA, et al. J Clin Endocrinol Metab. 2002 May;87(5):2150-9. doi: 10.1210/jcem.87.5.8441. J Clin Endocrinol Metab. 2002. PMID: 11994357

6

High prevalence of BRAF mutations in thyroid cancer: genetic evidence for constitutive activation of the RET/PTC-RAS-BRAF signaling pathway in papillary thyroid carcinoma.

Kimura ET, Nikiforova MN, Zhu Z, Knauf JA, Nikiforov YE, Fagin JA. Kimura ET, et al. Among authors: knauf ja. Cancer Res. 2003 Apr 1;63(7):1454-7. Cancer Res. 2003. PMID: 12670889

7

Conditional expression of RET/PTC induces a weak oncogenic drive in thyroid PCCL3 cells and inhibits thyrotropin action at multiple levels.

Wang J, Knauf JA, Basu S, Puxeddu E, Kuroda H, Santoro M, Fusco A, Fagin JA. Wang J, et al. Among authors: knauf ja. Mol Endocrinol. 2003 Jul;17(7):1425-36. doi: 10.1210/me.2003-0041. Epub 2003 Apr 10. Mol Endocrinol. 2003. PMID: 12690093

8

RET/PTC-induced dedifferentiation of thyroid cells is mediated through Y1062 signaling through SHC-RAS-MAP kinase.

Knauf JA, Kuroda H, Basu S, Fagin JA. Knauf JA, et al. Oncogene. 2003 Jul 10;22(28):4406-12. doi: 10.1038/sj.onc.1206602. Oncogene. 2003. PMID: 12853977

9

Acute expression of RET/PTC induces isozyme-specific activation and subsequent downregulation of PKCepsilon in PCCL3 thyroid cells.

Knauf JA, Ouyang B, Croyle M, Kimura E, Fagin JA. Knauf JA, et al. Oncogene. 2003 Oct 9;22(44):6830-8. doi: 10.1038/sj.onc.1206829. Oncogene. 2003. PMID: 14534528

10

Microsomal prostaglandin E2 synthase-1 is induced by conditional expression of RET/PTC in thyroid PCCL3 cells through the activation of the MEK-ERK pathway.

Puxeddu E, Mitsutake N, Knauf JA, Moretti S, Kim HW, Seta KA, Brockman D, Myatt L, Millhorn DE, Fagin JA. Puxeddu E, et al. Among authors: knauf ja. J Biol Chem. 2003 Dec 26;278(52):52131-8. doi: 10.1074/jbc.M306003200. Epub 2003 Oct 10. J Biol Chem. 2003. PMID: 14555660 Free article.

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