Xu J - Search Results

1

Inhibition of Aurora-A results in increased cell death in 3-dimensional culture microenvironment, reduced migration and is associated with enhanced radiosensitivity in human nasopharyngeal carcinoma.

Wan XB, Fan XJ, Chen MY, Xu J, Long ZJ, Hua YJ, Ji H, Liu L, Hong MH, Zeng YX, Liu Q. Wan XB, et al. Among authors: xu j. Cancer Biol Ther. 2009 Aug;8(15):1500-6. doi: 10.4161/cbt.8.15.8958. Epub 2009 Aug 8. Cancer Biol Ther. 2009. PMID: 19502819 Free article.

2

Aurora-A, a negative prognostic marker, increases migration and decreases radiosensitivity in cancer cells.

Guan Z, Wang XR, Zhu XF, Huang XF, Xu J, Wang LH, Wan XB, Long ZJ, Liu JN, Feng GK, Huang W, Zeng YX, Chen FJ, Liu Q. Guan Z, et al. Among authors: xu j. Cancer Res. 2007 Nov 1;67(21):10436-44. doi: 10.1158/0008-5472.CAN-07-1379. Cancer Res. 2007. PMID: 17974987

3

Aurora kinase small molecule inhibitor destroys mitotic spindle, suppresses cell growth, and induces apoptosis in oral squamous cancer cells.

Pan C, Yan M, Yao J, Xu J, Long Z, Huang H, Liu Q. Pan C, et al. Among authors: xu j. Oral Oncol. 2008 Jul;44(7):639-45. doi: 10.1016/j.oraloncology.2007.08.010. Epub 2007 Nov 8. Oral Oncol. 2008. PMID: 17996488

4

Aurora kinase inhibitory VX-680 increases Bax/Bcl-2 ratio and induces apoptosis in Aurora-A-high acute myeloid leukemia.

Huang XF, Luo SK, Xu J, Li J, Xu DR, Wang LH, Yan M, Wang XR, Wan XB, Zheng FM, Zeng YX, Liu Q. Huang XF, et al. Among authors: xu dr, xu j. Blood. 2008 Mar 1;111(5):2854-65. doi: 10.1182/blood-2007-07-099325. Epub 2007 Dec 26. Blood. 2008. PMID: 18160664 Free article.

5

ZM 447439 inhibition of aurora kinase induces Hep2 cancer cell apoptosis in three-dimensional culture.

Long ZJ, Xu J, Yan M, Zhang JG, Guan Z, Xu DZ, Wang XR, Yao J, Zheng FM, Chu GL, Cao JX, Zeng YX, Liu Q. Long ZJ, et al. Among authors: xu dz, xu j. Cell Cycle. 2008 May 15;7(10):1473-9. doi: 10.4161/cc.7.10.5949. Epub 2008 Mar 12. Cell Cycle. 2008. PMID: 18418083

6

Inhibition of Aurora-A suppresses epithelial-mesenchymal transition and invasion by downregulating MAPK in nasopharyngeal carcinoma cells.

Wan XB, Long ZJ, Yan M, Xu J, Xia LP, Liu L, Zhao Y, Huang XF, Wang XR, Zhu XF, Hong MH, Liu Q. Wan XB, et al. Among authors: xu j. Carcinogenesis. 2008 Oct;29(10):1930-7. doi: 10.1093/carcin/bgn176. Epub 2008 Jul 30. Carcinogenesis. 2008. PMID: 18667445

7

Aurora-A down-regulates IkappaBalpha via Akt activation and interacts with insulin-like growth factor-1 induced phosphatidylinositol 3-kinase pathway for cancer cell survival.

Yao JE, Yan M, Guan Z, Pan CB, Xia LP, Li CX, Wang LH, Long ZJ, Zhao Y, Li MW, Zheng FM, Xu J, Lin DJ, Liu Q. Yao JE, et al. Among authors: xu j. Mol Cancer. 2009 Nov 5;8:95. doi: 10.1186/1476-4598-8-95. Mol Cancer. 2009. PMID: 19891769 Free PMC article.

8

Elevated Beclin 1 expression is correlated with HIF-1alpha in predicting poor prognosis of nasopharyngeal carcinoma.

Wan XB, Fan XJ, Chen MY, Xiang J, Huang PY, Guo L, Wu XY, Xu J, Long ZJ, Zhao Y, Zhou WH, Mai HQ, Liu Q, Hong MH. Wan XB, et al. Among authors: xu j. Autophagy. 2010 Apr;6(3):395-404. doi: 10.4161/auto.6.3.11303. Epub 2010 Apr 26. Autophagy. 2010. PMID: 20150769 Clinical Trial.

9

A microfluidic demonstration of "cluster-sprout-infiltrating" mode for hypoxic mesenchymal stem cell guided cancer cell migration.

An F, Hou Z, Wang X, Wang Z, Jing C, Sui R, Wu Y, Ma Y, Chang C, Liu S, Li M, Sun L, Gao Z, Zhang W, Lang Z, Zhao J, Qu Y, Xu L, Luo Y, Yan J, Wang Y, Xu J, Liu Q. An F, et al. Among authors: xu l, xu j. Biomaterials. 2022 Nov;290:121848. doi: 10.1016/j.biomaterials.2022.121848. Epub 2022 Oct 14. Biomaterials. 2022. PMID: 36306684

10

Aurora kinase A-mediated phosphorylation triggers structural alteration of Rab1A to enhance ER complexity during mitosis.

Zhang W, Zhang Z, Xiang Y, Gu DD, Chen J, Chen Y, Zhai S, Liu Y, Jiang T, Liu C, He B, Yan M, Wang Z, Xu J, Cao YL, Deng B, Zeng D, Lei J, Zhuo J, Lei X, Long Z, Jin B, Chen T, Li D, Shen Y, Hu J, Gao S, Liu Q. Zhang W, et al. Among authors: xu j. Nat Struct Mol Biol. 2024 Feb;31(2):219-231. doi: 10.1038/s41594-023-01165-7. Epub 2024 Jan 4. Nat Struct Mol Biol. 2024. PMID: 38177680

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