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REL, encoding a member of the NF-kappaB family of transcription factors, is a newly defined risk locus for rheumatoid arthritis.
Gregersen PK, Amos CI, Lee AT, Lu Y, Remmers EF, Kastner DL, Seldin MF, Criswell LA, Plenge RM, Holers VM, Mikuls TR, Sokka T, Moreland LW, Bridges SL Jr, Xie G, Begovich AB, Siminovitch KA. Gregersen PK, et al. Among authors: amos ci. Nat Genet. 2009 Jul;41(7):820-3. doi: 10.1038/ng.395. Epub 2009 Jun 7. Nat Genet. 2009. PMID: 19503088 Free PMC article.
Dissecting the genetic complexity of the association between human leukocyte antigens and rheumatoid arthritis.
Jawaheer D, Li W, Graham RR, Chen W, Damle A, Xiao X, Monteiro J, Khalili H, Lee A, Lundsten R, Begovich A, Bugawan T, Erlich H, Elder JT, Criswell LA, Seldin MF, Amos CI, Behrens TW, Gregersen PK. Jawaheer D, et al. Among authors: amos ci. Am J Hum Genet. 2002 Sep;71(3):585-94. doi: 10.1086/342407. Epub 2002 Aug 9. Am J Hum Genet. 2002. PMID: 12181776 Free PMC article.
Screening the genome for rheumatoid arthritis susceptibility genes: a replication study and combined analysis of 512 multicase families.
Jawaheer D, Seldin MF, Amos CI, Chen WV, Shigeta R, Etzel C, Damle A, Xiao X, Chen D, Lum RF, Monteiro J, Kern M, Criswell LA, Albani S, Nelson JL, Clegg DO, Pope R, Schroeder HW Jr, Bridges SL Jr, Pisetsky DS, Ward R, Kastner DL, Wilder RL, Pincus T, Callahan LF, Flemming D, Wener MH, Gregersen PK; North American Rheumatoid Arthritis Consortium. Jawaheer D, et al. Among authors: amos ci. Arthritis Rheum. 2003 Apr;48(4):906-16. doi: 10.1002/art.10989. Arthritis Rheum. 2003. PMID: 12687532 Free article.
A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis.
Begovich AB, Carlton VE, Honigberg LA, Schrodi SJ, Chokkalingam AP, Alexander HC, Ardlie KG, Huang Q, Smith AM, Spoerke JM, Conn MT, Chang M, Chang SY, Saiki RK, Catanese JJ, Leong DU, Garcia VE, McAllister LB, Jeffery DA, Lee AT, Batliwalla F, Remmers E, Criswell LA, Seldin MF, Kastner DL, Amos CI, Sninsky JJ, Gregersen PK. Begovich AB, et al. Among authors: amos ci. Am J Hum Genet. 2004 Aug;75(2):330-7. doi: 10.1086/422827. Epub 2004 Jun 18. Am J Hum Genet. 2004. PMID: 15208781 Free PMC article.
Association of the lymphoid tyrosine phosphatase R620W variant with rheumatoid arthritis, but not Crohn's disease, in Canadian populations.
van Oene M, Wintle RF, Liu X, Yazdanpanah M, Gu X, Newman B, Kwan A, Johnson B, Owen J, Greer W, Mosher D, Maksymowych W, Keystone E, Rubin LA, Amos CI, Siminovitch KA. van Oene M, et al. Among authors: amos ci. Arthritis Rheum. 2005 Jul;52(7):1993-8. doi: 10.1002/art.21123. Arthritis Rheum. 2005. PMID: 15986374 Free article.
PTPN22 genetic variation: evidence for multiple variants associated with rheumatoid arthritis.
Carlton VE, Hu X, Chokkalingam AP, Schrodi SJ, Brandon R, Alexander HC, Chang M, Catanese JJ, Leong DU, Ardlie KG, Kastner DL, Seldin MF, Criswell LA, Gregersen PK, Beasley E, Thomson G, Amos CI, Begovich AB. Carlton VE, et al. Among authors: amos ci. Am J Hum Genet. 2005 Oct;77(4):567-81. doi: 10.1086/468189. Epub 2005 Aug 10. Am J Hum Genet. 2005. PMID: 16175503 Free PMC article.
Refining the complex rheumatoid arthritis phenotype based on specificity of the HLA-DRB1 shared epitope for antibodies to citrullinated proteins.
Huizinga TW, Amos CI, van der Helm-van Mil AH, Chen W, van Gaalen FA, Jawaheer D, Schreuder GM, Wener M, Breedveld FC, Ahmad N, Lum RF, de Vries RR, Gregersen PK, Toes RE, Criswell LA. Huizinga TW, et al. Among authors: amos ci. Arthritis Rheum. 2005 Nov;52(11):3433-8. doi: 10.1002/art.21385. Arthritis Rheum. 2005. PMID: 16255021 Free article.
858 results