Ten Dijke P - Search Results

1

Dominant-negative ALK2 allele associates with congenital heart defects.

Smith KA, Joziasse IC, Chocron S, van Dinther M, Guryev V, Verhoeven MC, Rehmann H, van der Smagt JJ, Doevendans PA, Cuppen E, Mulder BJ, Ten Dijke P, Bakkers J. Smith KA, et al. Among authors: ten dijke p. Circulation. 2009 Jun 23;119(24):3062-9. doi: 10.1161/CIRCULATIONAHA.108.843714. Epub 2009 Jun 8. Circulation. 2009. PMID: 19506109

2

RLP, a novel Ras-like protein, is an immediate-early transforming growth factor-beta (TGF-beta) target gene that negatively regulates transcriptional activity induced by TGF-beta.

Piek E, Van Dinther M, Parks WT, Sallee JM, Böttinger EP, Roberts AB, Ten Dijke P. Piek E, et al. Among authors: ten dijke p. Biochem J. 2004 Oct 1;383(Pt 1):187-99. doi: 10.1042/BJ20040774. Biochem J. 2004. PMID: 15239668 Free PMC article.

3

Connective tissue growth factor expression and Smad signaling during mouse heart development and myocardial infarction.

Chuva de Sousa Lopes SM, Feijen A, Korving J, Korchynskyi O, Larsson J, Karlsson S, ten Dijke P, Lyons KM, Goldschmeding R, Doevendans P, Mummery CL. Chuva de Sousa Lopes SM, et al. Among authors: ten dijke p. Dev Dyn. 2004 Nov;231(3):542-50. doi: 10.1002/dvdy.20162. Dev Dyn. 2004. PMID: 15376321 Free article.

4

The tumor suppressor Smad4 is required for transforming growth factor beta-induced epithelial to mesenchymal transition and bone metastasis of breast cancer cells.

Deckers M, van Dinther M, Buijs J, Que I, Löwik C, van der Pluijm G, ten Dijke P. Deckers M, et al. Among authors: ten dijke p. Cancer Res. 2006 Feb 15;66(4):2202-9. doi: 10.1158/0008-5472.CAN-05-3560. Cancer Res. 2006. PMID: 16489022

5

Endoglin has a crucial role in blood cell-mediated vascular repair.

van Laake LW, van den Driesche S, Post S, Feijen A, Jansen MA, Driessens MH, Mager JJ, Snijder RJ, Westermann CJ, Doevendans PA, van Echteld CJ, ten Dijke P, Arthur HM, Goumans MJ, Lebrin F, Mummery CL. van Laake LW, et al. Among authors: ten dijke p. Circulation. 2006 Nov 21;114(21):2288-97. doi: 10.1161/CIRCULATIONAHA.106.639161. Epub 2006 Nov 6. Circulation. 2006. PMID: 17088457

6

BMP-9 signals via ALK1 and inhibits bFGF-induced endothelial cell proliferation and VEGF-stimulated angiogenesis.

Scharpfenecker M, van Dinther M, Liu Z, van Bezooijen RL, Zhao Q, Pukac L, Löwik CW, ten Dijke P. Scharpfenecker M, et al. Among authors: ten dijke p. J Cell Sci. 2007 Mar 15;120(Pt 6):964-72. doi: 10.1242/jcs.002949. Epub 2007 Feb 20. J Cell Sci. 2007. PMID: 17311849

7

Oral administration of GW788388, an inhibitor of TGF-beta type I and II receptor kinases, decreases renal fibrosis.

Petersen M, Thorikay M, Deckers M, van Dinther M, Grygielko ET, Gellibert F, de Gouville AC, Huet S, ten Dijke P, Laping NJ. Petersen M, et al. Among authors: ten dijke p. Kidney Int. 2008 Mar;73(6):705-15. doi: 10.1038/sj.ki.5002717. Epub 2007 Dec 12. Kidney Int. 2008. PMID: 18075500 Free article.

8

Two novel type II receptors mediate BMP signalling and are required to establish left-right asymmetry in zebrafish.

Monteiro R, van Dinther M, Bakkers J, Wilkinson R, Patient R, ten Dijke P, Mummery C. Monteiro R, et al. Among authors: ten dijke p. Dev Biol. 2008 Mar 1;315(1):55-71. doi: 10.1016/j.ydbio.2007.11.038. Epub 2007 Dec 15. Dev Biol. 2008. PMID: 18222420 Free article.

9

VEGF and inhibitors of TGFbeta type-I receptor kinase synergistically promote blood-vessel formation by inducing alpha5-integrin expression.

Liu Z, Kobayashi K, van Dinther M, van Heiningen SH, Valdimarsdottir G, van Laar T, Scharpfenecker M, Löwik CW, Goumans MJ, Ten Dijke P, Pardali E. Liu Z, et al. Among authors: ten dijke p. J Cell Sci. 2009 Sep 15;122(Pt 18):3294-302. doi: 10.1242/jcs.048942. Epub 2009 Aug 25. J Cell Sci. 2009. PMID: 19706683

10

ALK2 R206H mutation linked to fibrodysplasia ossificans progressiva confers constitutive activity to the BMP type I receptor and sensitizes mesenchymal cells to BMP-induced osteoblast differentiation and bone formation.

van Dinther M, Visser N, de Gorter DJ, Doorn J, Goumans MJ, de Boer J, ten Dijke P. van Dinther M, et al. Among authors: ten dijke p. J Bone Miner Res. 2010 Jun;25(6):1208-15. doi: 10.1359/jbmr.091110. J Bone Miner Res. 2010. PMID: 19929436 Free article.

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