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The dorsal raphe nucleus shows phospho-tau neurofibrillary changes before the transentorhinal region in Alzheimer's disease. A precocious onset?
Grinberg LT, Rüb U, Ferretti RE, Nitrini R, Farfel JM, Polichiso L, Gierga K, Jacob-Filho W, Heinsen H; Brazilian Brain Bank Study Group. Grinberg LT, et al. Among authors: heinsen h. Neuropathol Appl Neurobiol. 2009 Aug;35(4):406-16. doi: 10.1111/j.1365-2990.2009.00997.x. Neuropathol Appl Neurobiol. 2009. PMID: 19508444
Quantifying the accretion of hyperphosphorylated tau in the locus coeruleus and dorsal raphe nucleus: the pathological building blocks of early Alzheimer's disease.
Ehrenberg AJ, Nguy AK, Theofilas P, Dunlop S, Suemoto CK, Di Lorenzo Alho AT, Leite RP, Diehl Rodriguez R, Mejia MB, Rüb U, Farfel JM, de Lucena Ferretti-Rebustini RE, Nascimento CF, Nitrini R, Pasquallucci CA, Jacob-Filho W, Miller B, Seeley WW, Heinsen H, Grinberg LT. Ehrenberg AJ, et al. Among authors: heinsen h. Neuropathol Appl Neurobiol. 2017 Aug;43(5):393-408. doi: 10.1111/nan.12387. Epub 2017 Mar 31. Neuropathol Appl Neurobiol. 2017. PMID: 28117917 Free PMC article.
Locus coeruleus volume and cell population changes during Alzheimer's disease progression: A stereological study in human postmortem brains with potential implication for early-stage biomarker discovery.
Theofilas P, Ehrenberg AJ, Dunlop S, Di Lorenzo Alho AT, Nguy A, Leite REP, Rodriguez RD, Mejia MB, Suemoto CK, Ferretti-Rebustini REL, Polichiso L, Nascimento CF, Seeley WW, Nitrini R, Pasqualucci CA, Jacob Filho W, Rueb U, Neuhaus J, Heinsen H, Grinberg LT. Theofilas P, et al. Among authors: heinsen h. Alzheimers Dement. 2017 Mar;13(3):236-246. doi: 10.1016/j.jalz.2016.06.2362. Epub 2016 Aug 8. Alzheimers Dement. 2017. PMID: 27513978 Free PMC article.
Probing the correlation of neuronal loss, neurofibrillary tangles, and cell death markers across the Alzheimer's disease Braak stages: a quantitative study in humans.
Theofilas P, Ehrenberg AJ, Nguy A, Thackrey JM, Dunlop S, Mejia MB, Alho AT, Paraizo Leite RE, Rodriguez RD, Suemoto CK, Nascimento CF, Chin M, Medina-Cleghorn D, Cuervo AM, Arkin M, Seeley WW, Miller BL, Nitrini R, Pasqualucci CA, Filho WJ, Rueb U, Neuhaus J, Heinsen H, Grinberg LT. Theofilas P, et al. Among authors: heinsen h. Neurobiol Aging. 2018 Jan;61:1-12. doi: 10.1016/j.neurobiolaging.2017.09.007. Epub 2017 Sep 20. Neurobiol Aging. 2018. PMID: 29031088 Free PMC article.
On the origin of tau seeding activity in Alzheimer's disease.
Heinsen H, Grinberg LT. Heinsen H, et al. Acta Neuropathol. 2018 Nov;136(5):815-817. doi: 10.1007/s00401-018-1890-3. Epub 2018 Jul 23. Acta Neuropathol. 2018. PMID: 30039213 Free PMC article. No abstract available.
Precortical Phase of Alzheimer's Disease (AD)-Related Tau Cytoskeletal Pathology.
Stratmann K, Heinsen H, Korf HW, Del Turco D, Ghebremedhin E, Seidel K, Bouzrou M, Grinberg LT, Bohl J, Wharton SB, den Dunnen W, Rüb U. Stratmann K, et al. Among authors: heinsen h. Brain Pathol. 2016 May;26(3):371-86. doi: 10.1111/bpa.12289. Epub 2015 Aug 24. Brain Pathol. 2016. PMID: 26193084 Free PMC article.
Pathoarchitectonics of the cerebral cortex in chorea-acanthocytosis and Huntington's disease.
Liu J, Heinsen H, Grinberg LT, Alho E, Amaro E Jr, Pasqualucci CA, Rüb U, Seidel K, den Dunnen W, Arzberger T, Schmitz C, Kiessling MC, Bader B, Danek A. Liu J, et al. Among authors: heinsen h. Neuropathol Appl Neurobiol. 2019 Apr;45(3):230-243. doi: 10.1111/nan.12495. Epub 2018 Jun 10. Neuropathol Appl Neurobiol. 2019. PMID: 29722054 Free PMC article.
A novel approach for integrative studies on neurodegenerative diseases in human brains.
Theofilas P, Polichiso L, Wang X, Lima LC, Alho ATL, Leite REP, Suemoto CK, Pasqualucci CA, Jacob-Filho W, Heinsen H; Brazilian Aging Brain Study Group; Grinberg LT. Theofilas P, et al. Among authors: heinsen h. J Neurosci Methods. 2014 Apr 15;226:171-183. doi: 10.1016/j.jneumeth.2014.01.030. Epub 2014 Feb 3. J Neurosci Methods. 2014. PMID: 24503023 Free PMC article.
195 results