Ohsugi T - Search Results

1

Biscoclaurine alkaloid cepharanthine inhibits the growth of primary effusion lymphoma in vitro and in vivo and induces apoptosis via suppression of the NF-kappaB pathway.

Takahashi-Makise N, Suzu S, Hiyoshi M, Ohsugi T, Katano H, Umezawa K, Okada S. Takahashi-Makise N, et al. Among authors: ohsugi t. Int J Cancer. 2009 Sep 15;125(6):1464-72. doi: 10.1002/ijc.24521. Int J Cancer. 2009. PMID: 19521981

2

In vivo antitumor activity of the NF-kappaB inhibitor dehydroxymethylepoxyquinomicin in a mouse model of adult T-cell leukemia.

Ohsugi T, Horie R, Kumasaka T, Ishida A, Ishida T, Yamaguchi K, Watanabe T, Umezawa K, Urano T. Ohsugi T, et al. Carcinogenesis. 2005 Aug;26(8):1382-8. doi: 10.1093/carcin/bgi095. Epub 2005 Apr 14. Carcinogenesis. 2005. PMID: 15831528

3

Dual targeting of transformed and untransformed HTLV-1-infected T cells by DHMEQ, a potent and selective inhibitor of NF-kappaB, as a strategy for chemoprevention and therapy of adult T-cell leukemia.

Watanabe M, Ohsugi T, Shoda M, Ishida T, Aizawa S, Maruyama-Nagai M, Utsunomiya A, Koga S, Yamada Y, Kamihira S, Okayama A, Kikuchi H, Uozumi K, Yamaguchi K, Higashihara M, Umezawa K, Watanabe T, Horie R. Watanabe M, et al. Among authors: ohsugi t. Blood. 2005 Oct 1;106(7):2462-71. doi: 10.1182/blood-2004-09-3646. Epub 2005 Jun 14. Blood. 2005. PMID: 15956280 Free article.

4

In vitro and in vivo antitumor activity of the NF-kappaB inhibitor DHMEQ in the human T-cell leukemia virus type I-infected cell line, HUT-102.

Ohsugi T, Kumasaka T, Ishida A, Ishida T, Horie R, Watanabe T, Umezawa K, Yamaguchi K. Ohsugi T, et al. Leuk Res. 2006 Jan;30(1):90-7. doi: 10.1016/j.leukres.2005.06.001. Epub 2005 Jul 5. Leuk Res. 2006. PMID: 16002138

5

The Tax protein of HTLV-1 promotes oncogenesis in not only immature T cells but also mature T cells.

Ohsugi T, Kumasaka T, Okada S, Urano T. Ohsugi T, et al. Nat Med. 2007 May;13(5):527-8. doi: 10.1038/nm0507-527. Nat Med. 2007. PMID: 17479090 No abstract available.

6

Dehydroxymethylepoxyquinomicin (DHMEQ) therapy reduces tumor formation in mice inoculated with tax-deficient adult T-cell leukemia-derived cell lines.

Ohsugi T, Kumasaka T, Okada S, Ishida T, Yamaguchi K, Horie R, Watanabe T, Umezawa K. Ohsugi T, et al. Cancer Lett. 2007 Nov 18;257(2):206-15. doi: 10.1016/j.canlet.2007.07.017. Epub 2007 Aug 30. Cancer Lett. 2007. PMID: 17764832

7

p53 dysfunction precedes the activation of nuclear factor-κB during disease progression in mice expressing Tax, a human T-cell leukemia virus type 1 oncoprotein.

Ohsugi T, Ishida T, Shimasaki T, Okada S, Umezawa K. Ohsugi T, et al. Carcinogenesis. 2013 Sep;34(9):2129-36. doi: 10.1093/carcin/bgt144. Epub 2013 Apr 30. Carcinogenesis. 2013. PMID: 23633516

8

Targeting Excessive EZH1 and EZH2 Activities for Abnormal Histone Methylation and Transcription Network in Malignant Lymphomas.

Yamagishi M, Hori M, Fujikawa D, Ohsugi T, Honma D, Adachi N, Katano H, Hishima T, Kobayashi S, Nakano K, Nakashima M, Iwanaga M, Utsunomiya A, Tanaka Y, Okada S, Tsukasaki K, Tobinai K, Araki K, Watanabe T, Uchimaru K. Yamagishi M, et al. Among authors: ohsugi t. Cell Rep. 2019 Nov 19;29(8):2321-2337.e7. doi: 10.1016/j.celrep.2019.10.083. Cell Rep. 2019. PMID: 31747604 Free article.

9

Current topics in prevention of human T-cell leukemia virus type i infection: NF-kappa B inhibitors and APOBEC3.

Ohsugi T, Koito A. Ohsugi T, et al. Int Rev Immunol. 2008;27(4):225-53. doi: 10.1080/08830180801939272. Int Rev Immunol. 2008. PMID: 18574738 Review.

10

Rapid tumor death model for evaluation of new therapeutic agents for adult T-cell leukemia.

Ohsugi T, Yamaguchi K, Kumasaka T, Ishida T, Horie R, Watanabe T, Sakio N, Fujimoto T, Sakamoto N, Urano T. Ohsugi T, et al. Lab Invest. 2004 Feb;84(2):263-6. doi: 10.1038/labinvest.3700034. Lab Invest. 2004. PMID: 14688803 Free article.

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