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CCR3 is a target for age-related macular degeneration diagnosis and therapy.
Takeda A, Baffi JZ, Kleinman ME, Cho WG, Nozaki M, Yamada K, Kaneko H, Albuquerque RJ, Dridi S, Saito K, Raisler BJ, Budd SJ, Geisen P, Munitz A, Ambati BK, Green MG, Ishibashi T, Wright JD, Humbles AA, Gerard CJ, Ogura Y, Pan Y, Smith JR, Grisanti S, Hartnett ME, Rothenberg ME, Ambati J. Takeda A, et al. Among authors: smith jr. Nature. 2009 Jul 9;460(7252):225-30. doi: 10.1038/nature08151. Epub 2009 Jun 14. Nature. 2009. PMID: 19525930 Free PMC article.
Sequence- and target-independent angiogenesis suppression by siRNA via TLR3.
Kleinman ME, Yamada K, Takeda A, Chandrasekaran V, Nozaki M, Baffi JZ, Albuquerque RJ, Yamasaki S, Itaya M, Pan Y, Appukuttan B, Gibbs D, Yang Z, Karikó K, Ambati BK, Wilgus TA, DiPietro LA, Sakurai E, Zhang K, Smith JR, Taylor EW, Ambati J. Kleinman ME, et al. Among authors: smith jr. Nature. 2008 Apr 3;452(7187):591-7. doi: 10.1038/nature06765. Epub 2008 Mar 26. Nature. 2008. PMID: 18368052 Free PMC article.
CD44 isoforms in human retinal and choroidal endothelial cells.
Chipps TJ, Appukuttan B, Pan Y, Smith JR. Chipps TJ, et al. Among authors: smith jr. Graefes Arch Clin Exp Ophthalmol. 2013 Apr;251(4):1245-6. doi: 10.1007/s00417-012-2103-8. Epub 2012 Aug 3. Graefes Arch Clin Exp Ophthalmol. 2013. PMID: 22865258 Free PMC article. No abstract available.
The related transcriptional enhancer factor-1 isoform, TEAD4(216), can repress vascular endothelial growth factor expression in mammalian cells.
Appukuttan B, McFarland TJ, Stempel A, Kassem JB, Hartzell M, Zhang Y, Bond D, West K, Wilson R, Stout A, Pan Y, Ilias H, Robertson K, Klein ML, Wilson D, Smith JR, Stout JT. Appukuttan B, et al. Among authors: smith jr. PLoS One. 2012;7(6):e31260. doi: 10.1371/journal.pone.0031260. Epub 2012 Jun 22. PLoS One. 2012. PMID: 22761647 Free PMC article.
Role of the retinal vascular endothelial cell in ocular disease.
Bharadwaj AS, Appukuttan B, Wilmarth PA, Pan Y, Stempel AJ, Chipps TJ, Benedetti EE, Zamora DO, Choi D, David LL, Smith JR. Bharadwaj AS, et al. Among authors: smith jr. Prog Retin Eye Res. 2013 Jan;32:102-80. doi: 10.1016/j.preteyeres.2012.08.004. Epub 2012 Sep 11. Prog Retin Eye Res. 2013. PMID: 22982179 Free PMC article. Review.
T cell-intrinsic role for Nod2 in protection against Th17-mediated uveitis.
Napier RJ, Lee EJ, Davey MP, Vance EE, Furtado JM, Snow PE, Samson KA, Lashley SJ, Brown BR, Horai R, Mattapallil MJ, Xu B, Callegan MC, Uebelhoer LS, Lancioni CL, Vehe RK, Binstadt BA, Smith JR, Caspi RR, Rosenzweig HL. Napier RJ, et al. Among authors: smith jr. Nat Commun. 2020 Oct 26;11(1):5406. doi: 10.1038/s41467-020-18961-0. Nat Commun. 2020. PMID: 33106495 Free PMC article.
5,173 results