Xu W - Search Results

1

Acyltransferase mediated polyketide release from a fungal megasynthase.

Xie X, Meehan MJ, Xu W, Dorrestein PC, Tang Y. Xie X, et al. Among authors: xu w. J Am Chem Soc. 2009 Jun 24;131(24):8388-9. doi: 10.1021/ja903203g. J Am Chem Soc. 2009. PMID: 19530726 Free PMC article.

2

Analysis of intact and dissected fungal polyketide synthase-nonribosomal peptide synthetase in vitro and in Saccharomyces cerevisiae.

Xu W, Cai X, Jung ME, Tang Y. Xu W, et al. J Am Chem Soc. 2010 Oct 6;132(39):13604-7. doi: 10.1021/ja107084d. J Am Chem Soc. 2010. PMID: 20828130 Free PMC article.

3

Structural analysis of protein-protein interactions in type I polyketide synthases.

Xu W, Qiao K, Tang Y. Xu W, et al. Crit Rev Biochem Mol Biol. 2013 Mar-Apr;48(2):98-122. doi: 10.3109/10409238.2012.745476. Epub 2012 Dec 19. Crit Rev Biochem Mol Biol. 2013. PMID: 23249187 Free PMC article. Review.

4

The fumagillin biosynthetic gene cluster in Aspergillus fumigatus encodes a cryptic terpene cyclase involved in the formation of β-trans-bergamotene.

Lin HC, Chooi YH, Dhingra S, Xu W, Calvo AM, Tang Y. Lin HC, et al. Among authors: xu w. J Am Chem Soc. 2013 Mar 27;135(12):4616-9. doi: 10.1021/ja312503y. Epub 2013 Mar 19. J Am Chem Soc. 2013. PMID: 23488861 Free PMC article.

5

Understanding Programming of Fungal Iterative Polyketide Synthases: The Biochemical Basis for Regioselectivity by the Methyltransferase Domain in the Lovastatin Megasynthase.

Cacho RA, Thuss J, Xu W, Sanichar R, Gao Z, Nguyen A, Vederas JC, Tang Y. Cacho RA, et al. Among authors: xu w. J Am Chem Soc. 2015 Dec 23;137(50):15688-91. doi: 10.1021/jacs.5b11814. Epub 2015 Dec 10. J Am Chem Soc. 2015. PMID: 26630357 Free PMC article.

6

Phenalenone Polyketide Cyclization Catalyzed by Fungal Polyketide Synthase and Flavin-Dependent Monooxygenase.

Gao SS, Duan A, Xu W, Yu P, Hang L, Houk KN, Tang Y. Gao SS, et al. Among authors: xu w. J Am Chem Soc. 2016 Mar 30;138(12):4249-59. doi: 10.1021/jacs.6b01528. Epub 2016 Mar 22. J Am Chem Soc. 2016. PMID: 26978228 Free PMC article.

7

Classification, prediction, and verification of the regioselectivity of fungal polyketide synthase product template domains.

Li Y, Image II, Xu W, Image I, Tang Y, Image I. Li Y, et al. Among authors: xu w. J Biol Chem. 2010 Jul 23;285(30):22764-73. doi: 10.1074/jbc.M110.128504. Epub 2010 May 17. J Biol Chem. 2010. PMID: 20479000 Free PMC article.

8

FT-ICR-MS characterization of intermediates in the biosynthesis of the α-methylbutyrate side chain of lovastatin by the 277 kDa polyketide synthase LovF.

Meehan MJ, Xie X, Zhao X, Xu W, Tang Y, Dorrestein PC. Meehan MJ, et al. Among authors: xu w. Biochemistry. 2011 Jan 18;50(2):287-99. doi: 10.1021/bi1014776. Epub 2010 Dec 22. Biochemistry. 2011. PMID: 21069965 Free PMC article.

9

A fungal nonribosomal peptide synthetase module that can synthesize thiopyrazines.

Qiao K, Zhou H, Xu W, Zhang W, Garg N, Tang Y. Qiao K, et al. Among authors: xu w. Org Lett. 2011 Apr 1;13(7):1758-61. doi: 10.1021/ol200288w. Epub 2011 Mar 8. Org Lett. 2011. PMID: 21384820 Free PMC article.

10

Crystal structure and biochemical studies of the trans-acting polyketide enoyl reductase LovC from lovastatin biosynthesis.

Ames BD, Nguyen C, Bruegger J, Smith P, Xu W, Ma S, Wong E, Wong S, Xie X, Li JW, Vederas JC, Tang Y, Tsai SC. Ames BD, et al. Among authors: xu w. Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):11144-9. doi: 10.1073/pnas.1113029109. Epub 2012 Jun 25. Proc Natl Acad Sci U S A. 2012. PMID: 22733743 Free PMC article.

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