Donowitz M - Search Results

1

NHERF3 (PDZK1) contributes to basal and calcium inhibition of NHE3 activity in Caco-2BBe cells.

Zachos NC, Li X, Kovbasnjuk O, Hogema B, Sarker R, Lee LJ, Li M, de Jonge H, Donowitz M. Zachos NC, et al. Among authors: donowitz m. J Biol Chem. 2009 Aug 28;284(35):23708-18. doi: 10.1074/jbc.M109.012641. Epub 2009 Jun 17. J Biol Chem. 2009. PMID: 19535329 Free PMC article.

2

Molecular physiology of intestinal Na+/H+ exchange.

Zachos NC, Tse M, Donowitz M. Zachos NC, et al. Among authors: donowitz m. Annu Rev Physiol. 2005;67:411-43. doi: 10.1146/annurev.physiol.67.031103.153004. Annu Rev Physiol. 2005. PMID: 15709964 Review.

3

cGMP inhibition of Na+/H+ antiporter 3 (NHE3) requires PDZ domain adapter NHERF2, a broad specificity protein kinase G-anchoring protein.

Cha B, Kim JH, Hut H, Hogema BM, Nadarja J, Zizak M, Cavet M, Lee-Kwon W, Lohmann SM, Smolenski A, Tse CM, Yun C, de Jonge HR, Donowitz M. Cha B, et al. Among authors: donowitz m. J Biol Chem. 2005 Apr 29;280(17):16642-50. doi: 10.1074/jbc.M500505200. Epub 2005 Feb 18. J Biol Chem. 2005. PMID: 15722341 Free article.

4

NHERF family and NHE3 regulation.

Donowitz M, Cha B, Zachos NC, Brett CL, Sharma A, Tse CM, Li X. Donowitz M, et al. J Physiol. 2005 Aug 15;567(Pt 1):3-11. doi: 10.1113/jphysiol.2005.090399. Epub 2005 May 19. J Physiol. 2005. PMID: 15905209 Free PMC article. Review.

5

Na+/H+ exchanger NHE3 activity and trafficking are lipid Raft-dependent.

Murtazina R, Kovbasnjuk O, Donowitz M, Li X. Murtazina R, et al. Among authors: donowitz m. J Biol Chem. 2006 Jun 30;281(26):17845-55. doi: 10.1074/jbc.M601740200. Epub 2006 Apr 27. J Biol Chem. 2006. PMID: 16648141 Free article.

J., Leung, G., Cheong, A., Louvard, D., and Donowitz, M. (2001) J. Physiol. (Lond.) 537, 537-552). Here, we examined the role of LR in NHE3 transport activity using a simpler system: opossum kidney (OK) cells (a renal proximal tubule epithelial cell line) containing …

J., Leung, G., Cheong, A., Louvard, D., and Donowitz, M. (2001) J. Physiol. (Lond.) 537, 537-552). Here, we examined the role …

6

Regulatory binding partners and complexes of NHE3.

Donowitz M, Li X. Donowitz M, et al. Physiol Rev. 2007 Jul;87(3):825-72. doi: 10.1152/physrev.00030.2006. Physiol Rev. 2007. PMID: 17615390 Free article. Review.

7

Casein kinase 2 binds to the C terminus of Na+/H+ exchanger 3 (NHE3) and stimulates NHE3 basal activity by phosphorylating a separate site in NHE3.

Sarker R, Grønborg M, Cha B, Mohan S, Chen Y, Pandey A, Litchfield D, Donowitz M, Li X. Sarker R, et al. Among authors: donowitz m. Mol Biol Cell. 2008 Sep;19(9):3859-70. doi: 10.1091/mbc.e08-01-0019. Epub 2008 Jul 9. Mol Biol Cell. 2008. PMID: 18614797 Free PMC article.

8

Elevated intracellular calcium stimulates NHE3 activity by an IKEPP (NHERF4) dependent mechanism.

Zachos NC, Hodson C, Kovbasnjuk O, Li X, Thelin WR, Cha B, Milgram S, Donowitz M. Zachos NC, et al. Among authors: donowitz m. Cell Physiol Biochem. 2008;22(5-6):693-704. doi: 10.1159/000185553. Epub 2008 Dec 9. Cell Physiol Biochem. 2008. PMID: 19088451 Free PMC article.

9

NHE3 regulatory complexes.

Donowitz M, Mohan S, Zhu CX, Chen TE, Lin R, Cha B, Zachos NC, Murtazina R, Sarker R, Li X. Donowitz M, et al. J Exp Biol. 2009 Jun;212(Pt 11):1638-46. doi: 10.1242/jeb.028605. J Exp Biol. 2009. PMID: 19448074 Free PMC article. Review.

10

Phospholipase C-gamma binds directly to the Na+/H+ exchanger 3 and is required for calcium regulation of exchange activity.

Zachos NC, van Rossum DB, Li X, Caraveo G, Sarker R, Cha B, Mohan S, Desiderio S, Patterson RL, Donowitz M. Zachos NC, et al. Among authors: donowitz m. J Biol Chem. 2009 Jul 17;284(29):19437-44. doi: 10.1074/jbc.M109.006098. Epub 2009 May 27. J Biol Chem. 2009. PMID: 19473983 Free PMC article.

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