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Page 1
Immunogenicity of novel DosR regulon-encoded candidate antigens of Mycobacterium tuberculosis in three high-burden populations in Africa.
Black GF, Thiel BA, Ota MO, Parida SK, Adegbola R, Boom WH, Dockrell HM, Franken KL, Friggen AH, Hill PC, Klein MR, Lalor MK, Mayanja H, Schoolnik G, Stanley K, Weldingh K, Kaufmann SH, Walzl G, Ottenhoff TH; GCGH Biomarkers for TB Consortium. Black GF, et al. Among authors: ottenhoff th. Clin Vaccine Immunol. 2009 Aug;16(8):1203-12. doi: 10.1128/CVI.00111-09. Epub 2009 Jun 24. Clin Vaccine Immunol. 2009. PMID: 19553548 Free PMC article.
Neutrophil degranulation, NETosis and platelet degranulation pathway genes are co-induced in whole blood up to six months before tuberculosis diagnosis.
Meier S, Seddon JA, Maasdorp E, Kleynhans L, du Plessis N, Loxton AG, Malherbe ST, Zak DE, Thompson E, Duffy FJ, Kaufmann SHE, Ottenhoff THM, Scriba TJ, Suliman S, Sutherland JS, Winter J, Kuivaniemi H, Walzl G, Tromp G; GC6-74 Consortium; Catalysis TB Biomarkers Consortium. Meier S, et al. PLoS One. 2022 Dec 1;17(12):e0278295. doi: 10.1371/journal.pone.0278295. eCollection 2022. PLoS One. 2022. PMID: 36454773 Free PMC article.
Impaired resolution of blood transcriptomes through tuberculosis treatment with diabetes comorbidity.
Eckold C, van Doorn CLR, Ruslami R, Ronacher K, Riza AL, van Veen S, Lee JS, Kumar V, Kerry-Barnard S, Malherbe ST, Kleynhans L, Stanley K, Joosten SA, Critchley JA, Hill PC, van Crevel R, Wijmenga C, Haks MC, Ioana M, Alisjahbana B, Walzl G, Ottenhoff THM, Dockrell HM, Vianello E, Cliff JM; TANDEM Consortium$. Eckold C, et al. Clin Transl Med. 2023 Sep;13(9):e1375. doi: 10.1002/ctm2.1375. Clin Transl Med. 2023. PMID: 37649224 Free PMC article.
Evaluation of PLGA, lipid-PLGA hybrid nanoparticles, and cationic pH-sensitive liposomes as tuberculosis vaccine delivery systems in a Mycobacterium tuberculosis challenge mouse model - A comparison.
Szachniewicz MM, Neustrup MA, van den Eeden SJF, van Meijgaarden KE, Franken KLMC, van Veen S, Koning RI, Limpens RWAL, Geluk A, Bouwstra JA, Ottenhoff THM. Szachniewicz MM, et al. Among authors: ottenhoff thm. Int J Pharm. 2024 Dec 5;666:124842. doi: 10.1016/j.ijpharm.2024.124842. Epub 2024 Oct 17. Int J Pharm. 2024. PMID: 39424087 Free article.
Mtb-Specific HLA-E-Restricted T Cells Are Induced during Mtb Infection but Not after BCG Administration in Non-Human Primates and Humans.
Voogd L, van Wolfswinkel M, Satti I, White AD, Dijkman K, Gela A, van Meijgaarden KE, Franken KLMC, Marshall JL, Ottenhoff THM, Scriba TJ, McShane H, Sharpe SA, Verreck FAW, Joosten SA. Voogd L, et al. Among authors: ottenhoff thm. Vaccines (Basel). 2024 Oct 1;12(10):1129. doi: 10.3390/vaccines12101129. Vaccines (Basel). 2024. PMID: 39460296 Free PMC article.
Intradermal versus subcutaneous immunization: Effects of administration route using a lipid-PLGA hybrid nanoparticle tuberculosis vaccine.
Szachniewicz MM, van den Eeden SJF, van Meijgaarden KE, Franken KLMC, van Veen S, Geluk A, Bouwstra JA, Ottenhoff THM. Szachniewicz MM, et al. Among authors: ottenhoff thm. Eur J Pharm Sci. 2024 Dec 20;205:106995. doi: 10.1016/j.ejps.2024.106995. Online ahead of print. Eur J Pharm Sci. 2024. PMID: 39710106 Free article.
Mtb HLA-E-tetramer-sorted CD8+ T cells have a diverse TCR repertoire.
Voogd L, Drittij AMHF, Dingenouts CKE, Franken KLMC, Unen VV, van Meijgaarden KE, Ruibal P, Hagedoorn RS, Leitner JA, Steinberger P, Heemskerk MHM, Davis MM, Scriba TJ, Ottenhoff THM, Joosten SA. Voogd L, et al. iScience. 2024 Feb 15;27(3):109233. doi: 10.1016/j.isci.2024.109233. eCollection 2024 Mar 15. iScience. 2024. PMID: 38439958 Free PMC article.
525 results