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Page 1
Muscle-specific deletion of carnitine acetyltransferase compromises glucose tolerance and metabolic flexibility.
Muoio DM, Noland RC, Kovalik JP, Seiler SE, Davies MN, DeBalsi KL, Ilkayeva OR, Stevens RD, Kheterpal I, Zhang J, Covington JD, Bajpeyi S, Ravussin E, Kraus W, Koves TR, Mynatt RL. Muoio DM, et al. Among authors: seiler se. Cell Metab. 2012 May 2;15(5):764-77. doi: 10.1016/j.cmet.2012.04.005. Cell Metab. 2012. PMID: 22560225 Free PMC article.
Obesity and lipid stress inhibit carnitine acetyltransferase activity.
Seiler SE, Martin OJ, Noland RC, Slentz DH, DeBalsi KL, Ilkayeva OR, An J, Newgard CB, Koves TR, Muoio DM. Seiler SE, et al. J Lipid Res. 2014 Apr;55(4):635-44. doi: 10.1194/jlr.M043448. Epub 2014 Jan 6. J Lipid Res. 2014. PMID: 24395925 Free PMC article.
Targeted metabolomics connects thioredoxin-interacting protein (TXNIP) to mitochondrial fuel selection and regulation of specific oxidoreductase enzymes in skeletal muscle.
DeBalsi KL, Wong KE, Koves TR, Slentz DH, Seiler SE, Wittmann AH, Ilkayeva OR, Stevens RD, Perry CG, Lark DS, Hui ST, Szweda L, Neufer PD, Muoio DM. DeBalsi KL, et al. Among authors: seiler se. J Biol Chem. 2014 Mar 21;289(12):8106-20. doi: 10.1074/jbc.M113.511535. Epub 2014 Jan 30. J Biol Chem. 2014. PMID: 24482226 Free PMC article.