Fioni A - Search Results

1

Structure-property relationships of a class of carbamate-based fatty acid amide hydrolase (FAAH) inhibitors: chemical and biological stability.

Vacondio F, Silva C, Lodola A, Fioni A, Rivara S, Duranti A, Tontini A, Sanchini S, Clapper JR, Piomelli D, Mor M, Tarzia G. Vacondio F, et al. Among authors: fioni a. ChemMedChem. 2009 Sep;4(9):1495-504. doi: 10.1002/cmdc.200900120. ChemMedChem. 2009. PMID: 19554599 Free PMC article.

2

Optimization of M₃ Antagonist-PDE4 Inhibitor (MAPI) Dual Pharmacology Molecules for the Treatment of COPD.

Rizzi A, Amari G, Pivetti F, Delcanale M, Amadei F, Pappani A, Fornasari L, Villetti G, Marchini G, Pisano AR, Pitozzi V, Pittelli MG, Trevisani M, Salvadori M, Cenacchi V, Fioni A, Puccini P, Civelli M, Patacchini R, Baker-Glenn C, Van de Poël H, Blackaby W, Nash K, Armani E. Rizzi A, et al. Among authors: fioni a. J Med Chem. 2023 Aug 24;66(16):11476-11497. doi: 10.1021/acs.jmedchem.3c01012. Epub 2023 Aug 10. J Med Chem. 2023. PMID: 37561958

3

Development and validation of a LC-MS method with electrospray ionization for the determination of the imidazole H3 antagonist ROS203 in rat plasma.

Vacondio F, Silva C, Fioni A, Mor M, Rivara M, Bordi F, Flammini L, Ballabeni V, Barocelli E. Vacondio F, et al. Among authors: fioni a. J Pharm Biomed Anal. 2008 Jan 7;46(1):200-5. doi: 10.1016/j.jpba.2007.09.010. Epub 2007 Sep 18. J Pharm Biomed Anal. 2008. PMID: 17959330

4

N-(Anilinoethyl)amides: design and synthesis of metabolically stable, selective melatonin receptor ligands.

Rivara S, Vacondio F, Fioni A, Silva C, Carmi C, Mor M, Lucini V, Pannacci M, Caronno A, Scaglione F, Gobbi G, Spadoni G, Bedini A, Orlando P, Lucarini S, Tarzia G. Rivara S, et al. Among authors: fioni a. ChemMedChem. 2009 Oct;4(10):1746-55. doi: 10.1002/cmdc.200900240. ChemMedChem. 2009. PMID: 19728346

5

N-(2-oxo-3-oxetanyl)carbamic acid esters as N-acylethanolamine acid amidase inhibitors: synthesis and structure-activity and structure-property relationships.

Duranti A, Tontini A, Antonietti F, Vacondio F, Fioni A, Silva C, Lodola A, Rivara S, Solorzano C, Piomelli D, Tarzia G, Mor M. Duranti A, et al. Among authors: fioni a. J Med Chem. 2012 May 24;55(10):4824-36. doi: 10.1021/jm300349j. Epub 2012 May 10. J Med Chem. 2012. PMID: 22515328

6

Pulmonary delivery of a p38 α/β MAP kinase inhibitor: bioanalytical method validation and biodistribution in rat plasma and respiratory tissues.

Marenghi G, Clementino AR, Fioni A, Buttini F, Sonvico F. Marenghi G, et al. Among authors: fioni a. Eur J Pharm Sci. 2020 Apr 17;149:105341. doi: 10.1016/j.ejps.2020.105341. Online ahead of print. Eur J Pharm Sci. 2020. PMID: 32305320

7

Novel Pyrrolidine Derivatives of Budesonide as Long Acting Inhaled Corticosteroids for the Treatment of Pulmonary Inflammatory Diseases.

Ghidini E, Marchini G, Capelli AM, Carnini C, Cenacchi V, Fioni A, Facchinetti F, Rancati F. Ghidini E, et al. Among authors: fioni a. J Med Chem. 2018 Jun 14;61(11):4757-4773. doi: 10.1021/acs.jmedchem.7b01873. Epub 2018 May 24. J Med Chem. 2018. PMID: 29741897

8

Virtual screening using PLS discriminant analysis and ROC curve approach: an application study on PDE4 inhibitors.

Rizzi A, Fioni A. Rizzi A, et al. Among authors: fioni a. J Chem Inf Model. 2008 Aug;48(8):1686-92. doi: 10.1021/ci800072r. Epub 2008 Aug 1. J Chem Inf Model. 2008. PMID: 18671384

9

Investigation of Lung Pharmacokinetic of the Novel PDE4 Inhibitor CHF6001 in Preclinical Models: Evaluation of the PreciseInhale Technology.

Fioni A, Selg E, Cenacchi V, Acevedo F, Brogin G, Gerde P, Puccini P. Fioni A, et al. J Aerosol Med Pulm Drug Deliv. 2018 Feb;31(1):61-70. doi: 10.1089/jamp.2017.1369. Epub 2017 Aug 2. J Aerosol Med Pulm Drug Deliv. 2018. PMID: 28768120

10

Discovery and Optimization of Pyridazinones as PI3Kδ Selective Inhibitors for Administration by Inhalation.

Bruno P, Micoli A, Corsi M, Pala D, Guariento S, Fiorelli C, Ronchi P, Fioni A, Gallo PM, Marenghi G, Bertolini S, Capacchi S, Mileo V, Biagetti M, Capelli AM. Bruno P, et al. Among authors: fioni a. J Med Chem. 2024 Jul 11;67(13):11103-11124. doi: 10.1021/acs.jmedchem.4c00610. Epub 2024 Jun 22. J Med Chem. 2024. PMID: 38907711

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