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Proinflammatory cytokines activate the intrinsic apoptotic pathway in beta-cells.
Grunnet LG, Aikin R, Tonnesen MF, Paraskevas S, Blaabjerg L, Størling J, Rosenberg L, Billestrup N, Maysinger D, Mandrup-Poulsen T. Grunnet LG, et al. Among authors: tonnesen mf. Diabetes. 2009 Aug;58(8):1807-15. doi: 10.2337/db08-0178. Epub 2009 May 26. Diabetes. 2009. PMID: 19470609 Free PMC article.
Divalent metal transporter 1 regulates iron-mediated ROS and pancreatic β cell fate in response to cytokines.
Hansen JB, Tonnesen MF, Madsen AN, Hagedorn PH, Friberg J, Grunnet LG, Heller RS, Nielsen AØ, Størling J, Baeyens L, Anker-Kitai L, Qvortrup K, Bouwens L, Efrat S, Aalund M, Andrews NC, Billestrup N, Karlsen AE, Holst B, Pociot F, Mandrup-Poulsen T. Hansen JB, et al. Among authors: tonnesen mf. Cell Metab. 2012 Oct 3;16(4):449-61. doi: 10.1016/j.cmet.2012.09.001. Epub 2012 Sep 20. Cell Metab. 2012. PMID: 23000401 Free article.
RNA modifications by oxidation: a novel disease mechanism?
Poulsen HE, Specht E, Broedbaek K, Henriksen T, Ellervik C, Mandrup-Poulsen T, Tonnesen M, Nielsen PE, Andersen HU, Weimann A. Poulsen HE, et al. Free Radic Biol Med. 2012 Apr 15;52(8):1353-61. doi: 10.1016/j.freeradbiomed.2012.01.009. Epub 2012 Jan 28. Free Radic Biol Med. 2012. PMID: 22306201 Review.
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