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Retinoblastoma treatment: utilization of the glycolytic inhibitor, 2-deoxy-2-fluoro-D-glucose (2-FG), to target the chemoresistant hypoxic regions in LH(BETA)T(AG) retinal tumors.
Piña Y, Decatur C, Murray TG, Houston SK, Lopez-Cavalcante M, Hernandez E, Celdran M, Shah N, Feuer W, Lampidis T. Piña Y, et al. Invest Ophthalmol Vis Sci. 2012 Feb 27;53(2):996-1002. doi: 10.1167/iovs.11-8265. Print 2012 Feb. Invest Ophthalmol Vis Sci. 2012. PMID: 22266512 Free PMC article.
Novel retinoblastoma treatment avoids chemotherapy: the effect of optimally timed combination therapy with angiogenic and glycolytic inhibitors on LH(BETA)T(AG) retinoblastoma tumors.
Houston SK, Piña Y, Murray TG, Boutrid H, Cebulla C, Schefler AC, Shi W, Celdran M, Feuer W, Merchan J, Lampidis TJ. Houston SK, et al. Among authors: lampidis tj. Clin Ophthalmol. 2011 Jan 27;5:129-37. doi: 10.2147/OPTH.S15179. Clin Ophthalmol. 2011. PMID: 21339806 Free PMC article.
Targeting hypoxia, a novel treatment for advanced retinoblastoma.
Boutrid H, Jockovich ME, Murray TG, Piña Y, Feuer WJ, Lampidis TJ, Cebulla CM. Boutrid H, et al. Among authors: lampidis tj. Invest Ophthalmol Vis Sci. 2008 Jul;49(7):2799-805. doi: 10.1167/iovs.08-1751. Epub 2008 Mar 7. Invest Ophthalmol Vis Sci. 2008. PMID: 18326690
Antiangiogenic activity of 2-deoxy-D-glucose.
Merchan JR, Kovács K, Railsback JW, Kurtoglu M, Jing Y, Piña Y, Gao N, Murray TG, Lehrman MA, Lampidis TJ. Merchan JR, et al. Among authors: lampidis tj. PLoS One. 2010 Oct 27;5(10):e13699. doi: 10.1371/journal.pone.0013699. PLoS One. 2010. PMID: 21060881 Free PMC article.
89 results