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Small-molecule XIAP inhibitors derepress downstream effector caspases and induce apoptosis of acute myeloid leukemia cells.
Carter BZ, Gronda M, Wang Z, Welsh K, Pinilla C, Andreeff M, Schober WD, Nefzi A, Pond GR, Mawji IA, Houghten RA, Ostresh J, Brandwein J, Minden MD, Schuh AC, Wells RA, Messner H, Chun K, Reed JC, Schimmer AD. Carter BZ, et al. Among authors: schimmer ad. Blood. 2005 May 15;105(10):4043-50. doi: 10.1182/blood-2004-08-3168. Epub 2005 Feb 1. Blood. 2005. PMID: 15687241 Free PMC article.
Targeting XIAP for the treatment of malignancy.
Schimmer AD, Dalili S, Batey RA, Riedl SJ. Schimmer AD, et al. Cell Death Differ. 2006 Feb;13(2):179-88. doi: 10.1038/sj.cdd.4401826. Cell Death Differ. 2006. PMID: 16322751 Review.
Critical role for Fas-associated death domain-like interleukin-1-converting enzyme-like inhibitory protein in anoikis resistance and distant tumor formation.
Mawji IA, Simpson CD, Hurren R, Gronda M, Williams MA, Filmus J, Jonkman J, Da Costa RS, Wilson BC, Thomas MP, Reed JC, Glinsky GV, Schimmer AD. Mawji IA, et al. Among authors: schimmer ad. J Natl Cancer Inst. 2007 May 16;99(10):811-22. doi: 10.1093/jnci/djk182. J Natl Cancer Inst. 2007. PMID: 17505076
A chemical biology screen identifies glucocorticoids that regulate c-maf expression by increasing its proteasomal degradation through up-regulation of ubiquitin.
Mao X, Stewart AK, Hurren R, Datti A, Zhu X, Zhu Y, Shi C, Lee K, Tiedemann R, Eberhard Y, Trudel S, Liang S, Corey SJ, Gillis LC, Barber DL, Wrana JL, Ezzat S, Schimmer AD. Mao X, et al. Among authors: schimmer ad. Blood. 2007 Dec 1;110(12):4047-54. doi: 10.1182/blood-2007-05-088666. Epub 2007 Sep 17. Blood. 2007. PMID: 17875808 Free article.
299 results