Wernig M - Search Results

1

Cardiac myocytes derived from murine reprogrammed fibroblasts: intact hormonal regulation, cardiac ion channel expression and development of contractility.

Pfannkuche K, Liang H, Hannes T, Xi J, Fatima A, Nguemo F, Matzkies M, Wernig M, Jaenisch R, Pillekamp F, Halbach M, Schunkert H, Sarić T, Hescheler J, Reppel M. Pfannkuche K, et al. Among authors: wernig m. Cell Physiol Biochem. 2009;24(1-2):73-86. doi: 10.1159/000227815. Epub 2009 Jul 1. Cell Physiol Biochem. 2009. PMID: 19590195

2

Insights and applications of direct neuronal reprogramming.

Schaukowitch K, Janas JA, Wernig M. Schaukowitch K, et al. Among authors: wernig m. Curr Opin Genet Dev. 2023 Dec;83:102128. doi: 10.1016/j.gde.2023.102128. Epub 2023 Oct 18. Curr Opin Genet Dev. 2023. PMID: 37862835 Free PMC article. Review.

3

Tip60-mediated H2A.Z acetylation promotes neuronal fate specification and bivalent gene activation.

Janas JA, Zhang L, Luu JH, Demeter J, Meng L, Marro SG, Mall M, Mooney NA, Schaukowitch K, Ng YH, Yang N, Huang Y, Neumayer G, Gozani O, Elias JE, Jackson PK, Wernig M. Janas JA, et al. Among authors: wernig m. Mol Cell. 2022 Dec 15;82(24):4627-4646.e14. doi: 10.1016/j.molcel.2022.11.002. Epub 2022 Nov 22. Mol Cell. 2022. PMID: 36417913 Free PMC article.

4

Efficient generation of functional neurons from mouse embryonic stem cells via neurogenin-2 expression.

Liu Y, Wang J, Südhof TC, Wernig M. Liu Y, et al. Among authors: wernig m. Nat Protoc. 2023 Oct;18(10):2954-2974. doi: 10.1038/s41596-023-00863-2. Epub 2023 Aug 18. Nat Protoc. 2023. PMID: 37596357 Free PMC article. Review.

5

A cell therapy approach to restore microglial Trem2 function in a mouse model of Alzheimer's disease.

Yoo Y, Neumayer G, Shibuya Y, Mader MM, Wernig M. Yoo Y, et al. Among authors: wernig m. Cell Stem Cell. 2023 Aug 3;30(8):1043-1053.e6. doi: 10.1016/j.stem.2023.07.006. Cell Stem Cell. 2023. PMID: 37541210 Free article.

6

The autism risk factor CHD8 is a chromatin activator in human neurons and functionally dependent on the ERK-MAPK pathway effector ELK1.

Haddad Derafshi B, Danko T, Chanda S, Batista PJ, Litzenburger U, Lee QY, Ng YH, Sebin A, Chang HY, Südhof TC, Wernig M. Haddad Derafshi B, et al. Among authors: wernig m. Sci Rep. 2022 Dec 27;12(1):22425. doi: 10.1038/s41598-022-23614-x. Sci Rep. 2022. PMID: 36575212 Free PMC article.

7

Directly induced human retinal ganglion cells mimic fetal RGCs and are neuroprotective after transplantation in vivo.

Luo Z, Chang KC, Wu S, Sun C, Xia X, Nahmou M, Bian M, Wen RR, Zhu Y, Shah S, Tanasa B, Wernig M, Goldberg JL. Luo Z, et al. Among authors: wernig m. Stem Cell Reports. 2022 Dec 13;17(12):2690-2703. doi: 10.1016/j.stemcr.2022.10.011. Epub 2022 Nov 10. Stem Cell Reports. 2022. PMID: 36368332 Free PMC article.

8

Ascl1 and Ngn2 convert mouse embryonic stem cells to neurons via functionally distinct paths.

Vainorius G, Novatchkova M, Michlits G, Baar JC, Raupach C, Lee J, Yelagandula R, Wernig M, Elling U. Vainorius G, et al. Among authors: wernig m. Nat Commun. 2023 Sep 2;14(1):5341. doi: 10.1038/s41467-023-40803-y. Nat Commun. 2023. PMID: 37660160 Free PMC article.

9

Stress response silencing by an E3 ligase mutated in neurodegeneration.

Haakonsen DL, Heider M, Ingersoll AJ, Vodehnal K, Witus SR, Uenaka T, Wernig M, Rapé M. Haakonsen DL, et al. Among authors: wernig m. Nature. 2024 Feb;626(8000):874-880. doi: 10.1038/s41586-023-06985-7. Epub 2024 Jan 31. Nature. 2024. PMID: 38297121 Free PMC article.

10

Polycomb complexes repress developmental regulators in murine embryonic stem cells.

Boyer LA, Plath K, Zeitlinger J, Brambrink T, Medeiros LA, Lee TI, Levine SS, Wernig M, Tajonar A, Ray MK, Bell GW, Otte AP, Vidal M, Gifford DK, Young RA, Jaenisch R. Boyer LA, et al. Among authors: wernig m. Nature. 2006 May 18;441(7091):349-53. doi: 10.1038/nature04733. Epub 2006 Apr 19. Nature. 2006. PMID: 16625203

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