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Polymorphic variability in the interleukin (IL)-1beta promoter conditions susceptibility to severe malarial anemia and functional changes in IL-1beta production.
Ouma C, Davenport GC, Awandare GA, Keller CC, Were T, Otieno MF, Vulule JM, Martinson J, Ong'echa JM, Ferrell RE, Perkins DJ. Ouma C, et al. Among authors: were t. J Infect Dis. 2008 Oct 15;198(8):1219-26. doi: 10.1086/592055. J Infect Dis. 2008. PMID: 18781863 Free PMC article.
Because the role played by IL-1beta polymorphic variability in conditioning the immunopathogenesis of severe malarial anemia (SMA) remains undefined, relationships between IL-1beta promoter variants (-31C/T and -511A/G), SMA (hemoglobin [Hb] level <6.0 g/dL), and circul …
Because the role played by IL-1beta polymorphic variability in conditioning the immunopathogenesis of severe malarial anemia (SMA) remains u …
A novel functional variant in the stem cell growth factor promoter protects against severe malarial anemia.
Ouma C, Keller CC, Davenport GC, Were T, Konah S, Otieno MF, Hittner JB, Vulule JM, Martinson J, Ong'echa JM, Ferrell RE, Perkins DJ. Ouma C, et al. Among authors: were t. Infect Immun. 2010 Jan;78(1):453-60. doi: 10.1128/IAI.00895-09. Epub 2009 Nov 2. Infect Immun. 2010. PMID: 19884328 Free PMC article.

To extend these investigations, the relationships between a novel SCGF promoter variant (-539C/T, rs7246355), SMA (hemoglobin [Hb] < 6.0 g/dl), and reduced erythropoietic responses (reticulocyte production index [RPI], <2.0) were investigated with Kenyan child

…
To extend these investigations, the relationships between a novel SCGF promoter variant (-539C/T, rs7246355), SMA (hemoglobin [Hb] &l …
52 results