Al-Abed Y - Search Results

1

The selective alpha7 agonist GTS-21 attenuates cytokine production in human whole blood and human monocytes activated by ligands for TLR2, TLR3, TLR4, TLR9, and RAGE.

Rosas-Ballina M, Goldstein RS, Gallowitsch-Puerta M, Yang L, Valdés-Ferrer SI, Patel NB, Chavan S, Al-Abed Y, Yang H, Tracey KJ. Rosas-Ballina M, et al. Mol Med. 2009 Jul-Aug;15(7-8):195-202. doi: 10.2119/molmed.2009.00039. Epub 2009 Apr 27. Mol Med. 2009. PMID: 19593403 Free PMC article.

2

Cerebral ischemia enhances polyamine oxidation: identification of enzymatically formed 3-aminopropanal as an endogenous mediator of neuronal and glial cell death.

Ivanova S, Botchkina GI, Al-Abed Y, Meistrell M 3rd, Batliwalla F, Dubinsky JM, Iadecola C, Wang H, Gregersen PK, Eaton JW, Tracey KJ. Ivanova S, et al. J Exp Med. 1998 Jul 20;188(2):327-40. doi: 10.1084/jem.188.2.327. J Exp Med. 1998. PMID: 9670045 Free PMC article.

3

Neuroprotection in cerebral ischemia by neutralization of 3-aminopropanal.

Ivanova S, Batliwalla F, Mocco J, Kiss S, Huang J, Mack W, Coon A, Eaton JW, Al-Abed Y, Gregersen PK, Shohami E, Connolly ES Jr, Tracey KJ. Ivanova S, et al. Proc Natl Acad Sci U S A. 2002 Apr 16;99(8):5579-84. doi: 10.1073/pnas.082609299. Epub 2002 Apr 9. Proc Natl Acad Sci U S A. 2002. PMID: 11943872 Free PMC article.

4

Nicotinic acetylcholine receptor alpha7 subunit is an essential regulator of inflammation.

Wang H, Yu M, Ochani M, Amella CA, Tanovic M, Susarla S, Li JH, Wang H, Yang H, Ulloa L, Al-Abed Y, Czura CJ, Tracey KJ. Wang H, et al. Nature. 2003 Jan 23;421(6921):384-8. doi: 10.1038/nature01339. Epub 2002 Dec 22. Nature. 2003. PMID: 12508119

5

Cholinergic agonists inhibit HMGB1 release and improve survival in experimental sepsis.

Wang H, Liao H, Ochani M, Justiniani M, Lin X, Yang L, Al-Abed Y, Wang H, Metz C, Miller EJ, Tracey KJ, Ulloa L. Wang H, et al. Nat Med. 2004 Nov;10(11):1216-21. doi: 10.1038/nm1124. Epub 2004 Oct 24. Nat Med. 2004. PMID: 15502843 Free article.

6

Cholinergic stimulation blocks endothelial cell activation and leukocyte recruitment during inflammation.

Saeed RW, Varma S, Peng-Nemeroff T, Sherry B, Balakhaneh D, Huston J, Tracey KJ, Al-Abed Y, Metz CN. Saeed RW, et al. J Exp Med. 2005 Apr 4;201(7):1113-23. doi: 10.1084/jem.20040463. J Exp Med. 2005. PMID: 15809354 Free PMC article.

7

Alpha-chemokine receptor blockade reduces high mobility group box 1 protein-induced lung inflammation and injury and improves survival in sepsis.

Lin X, Yang H, Sakuragi T, Hu M, Mantell LL, Hayashi S, Al-Abed Y, Tracey KJ, Ulloa L, Miller EJ. Lin X, et al. Am J Physiol Lung Cell Mol Physiol. 2005 Oct;289(4):L583-90. doi: 10.1152/ajplung.00091.2005. Epub 2005 Jun 3. Am J Physiol Lung Cell Mol Physiol. 2005. PMID: 15937067 Free article.

8

ISO-1 binding to the tautomerase active site of MIF inhibits its pro-inflammatory activity and increases survival in severe sepsis.

Al-Abed Y, Dabideen D, Aljabari B, Valster A, Messmer D, Ochani M, Tanovic M, Ochani K, Bacher M, Nicoletti F, Metz C, Pavlov VA, Miller EJ, Tracey KJ. Al-Abed Y, et al. J Biol Chem. 2005 Nov 4;280(44):36541-4. doi: 10.1074/jbc.C500243200. Epub 2005 Aug 22. J Biol Chem. 2005. PMID: 16115897 Free article.

9

Central muscarinic cholinergic regulation of the systemic inflammatory response during endotoxemia.

Pavlov VA, Ochani M, Gallowitsch-Puerta M, Ochani K, Huston JM, Czura CJ, Al-Abed Y, Tracey KJ. Pavlov VA, et al. Proc Natl Acad Sci U S A. 2006 Mar 28;103(13):5219-23. doi: 10.1073/pnas.0600506103. Epub 2006 Mar 20. Proc Natl Acad Sci U S A. 2006. PMID: 16549778 Free PMC article.

10

Selective alpha7-nicotinic acetylcholine receptor agonist GTS-21 improves survival in murine endotoxemia and severe sepsis.

Pavlov VA, Ochani M, Yang LH, Gallowitsch-Puerta M, Ochani K, Lin X, Levi J, Parrish WR, Rosas-Ballina M, Czura CJ, Larosa GJ, Miller EJ, Tracey KJ, Al-Abed Y. Pavlov VA, et al. Crit Care Med. 2007 Apr;35(4):1139-44. doi: 10.1097/01.CCM.0000259381.56526.96. Crit Care Med. 2007. PMID: 17334244

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