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3,480 results

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Page 1
Discovery of tetrasubstituted imidazolines as potent and selective neuropeptide Y Y5 receptor antagonists: reduced human ether-a-go-go related gene potassium channel binding affinity and potent antiobesity effect.
Sato N, Ando M, Ishikawa S, Jitsuoka M, Nagai K, Takahashi H, Sakuraba A, Tsuge H, Kitazawa H, Iwaasa H, Mashiko S, Gomori A, Moriya R, Fujino N, Ohe T, Ishihara A, Kanatani A, Fukami T. Sato N, et al. Among authors: ando m. J Med Chem. 2009 May 28;52(10):3385-96. doi: 10.1021/jm900110t. J Med Chem. 2009. PMID: 19459652
Optimization of a series of 2,4-diaminopyridines as neuropeptide Y Y1 receptor antagonists with reduced hERG activity.
Kameda M, Kobayashi K, Ito H, Miyazoe H, Tsujino T, Nakama C, Kawamoto H, Ando M, Ito S, Suzuki T, Kanno T, Tanaka T, Tahara Y, Tani T, Tanaka S, Tokita S, Sato N. Kameda M, et al. Among authors: ando m. Bioorg Med Chem Lett. 2009 Aug 1;19(15):4325-9. doi: 10.1016/j.bmcl.2009.05.069. Epub 2009 May 24. Bioorg Med Chem Lett. 2009. PMID: 19487123
Discovery of pyridone-containing imidazolines as potent and selective inhibitors of neuropeptide Y Y5 receptor.
Ando M, Sato N, Nagase T, Nagai K, Ishikawa S, Takahashi H, Ohtake N, Ito J, Hirayama M, Mitobe Y, Iwaasa H, Gomori A, Matsushita H, Tadano K, Fujino N, Tanaka S, Ohe T, Ishihara A, Kanatani A, Fukami T. Ando M, et al. Bioorg Med Chem. 2009 Aug 15;17(16):6106-22. doi: 10.1016/j.bmc.2009.05.069. Epub 2009 Jun 2. Bioorg Med Chem. 2009. PMID: 19616955
Discovery of novel diarylketoxime derivatives as selective and orally active melanin-concentrating hormone 1 receptor antagonists.
Suzuki T, Kameda M, Ando M, Miyazoe H, Sekino E, Ito S, Masutani K, Kamijo K, Takezawa A, Moriya M, Ito M, Ito J, Nakase K, Matsushita H, Ishihara A, Takenaga N, Tokita S, Kanatani A, Sato N, Fukami T. Suzuki T, et al. Among authors: ando m. Bioorg Med Chem Lett. 2009 Sep 15;19(18):5339-45. doi: 10.1016/j.bmcl.2009.07.132. Epub 2009 Aug 6. Bioorg Med Chem Lett. 2009. PMID: 19683441
(9S)-9-(2-hydroxy-4,4-dimethyl-6-oxo-1-cyclohexen-1-yl)-3,3-dimethyl-2,3,4,9-tetrahydro-1H-xanthen-1-one, a selective and orally active neuropeptide Y Y5 receptor antagonist.
Sato N, Jitsuoka M, Shibata T, Hirohashi T, Nonoshita K, Moriya M, Haga Y, Sakuraba A, Ando M, Ohe T, Iwaasa H, Gomori A, Ishihara A, Kanatani A, Fukami T. Sato N, et al. Among authors: ando m. J Med Chem. 2008 Aug 14;51(15):4765-70. doi: 10.1021/jm8003587. Epub 2008 Jul 19. J Med Chem. 2008. PMID: 18637668
3,480 results