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Fulvene-5 potently inhibits NADPH oxidase 4 and blocks the growth of endothelial tumors in mice.
Bhandarkar SS, Jaconi M, Fried LE, Bonner MY, Lefkove B, Govindarajan B, Perry BN, Parhar R, Mackelfresh J, Sohn A, Stouffs M, Knaus U, Yancopoulos G, Reiss Y, Benest AV, Augustin HG, Arbiser JL. Bhandarkar SS, et al. Among authors: augustin hg. J Clin Invest. 2009 Aug;119(8):2359-65. doi: 10.1172/JCI33877. Epub 2009 Jul 13. J Clin Invest. 2009. PMID: 19620773 Free PMC article.
Cancer: Blood vessels kept quiet.
Benest AV, Augustin HG. Benest AV, et al. Among authors: augustin hg. Nature. 2009 Mar 5;458(7234):41-2. doi: 10.1038/458041a. Nature. 2009. PMID: 19262662 No abstract available.
Angiopoietin-2 is critical for cytokine-induced vascular leakage.
Benest AV, Kruse K, Savant S, Thomas M, Laib AM, Loos EK, Fiedler U, Augustin HG. Benest AV, et al. Among authors: augustin hg. PLoS One. 2013 Aug 5;8(8):e70459. doi: 10.1371/journal.pone.0070459. Print 2013. PLoS One. 2013. PMID: 23940579 Free PMC article.
Tension in the vasculature.
Benest AV, Augustin HG. Benest AV, et al. Among authors: augustin hg. Nat Med. 2009 Jun;15(6):608-10. doi: 10.1038/nm0609-608. Nat Med. 2009. PMID: 19498370 No abstract available.
The Orphan Receptor Tie1 Controls Angiogenesis and Vascular Remodeling by Differentially Regulating Tie2 in Tip and Stalk Cells.
Savant S, La Porta S, Budnik A, Busch K, Hu J, Tisch N, Korn C, Valls AF, Benest AV, Terhardt D, Qu X, Adams RH, Baldwin HS, Ruiz de Almodóvar C, Rodewald HR, Augustin HG. Savant S, et al. Among authors: augustin hg. Cell Rep. 2015 Sep 22;12(11):1761-73. doi: 10.1016/j.celrep.2015.08.024. Epub 2015 Sep 3. Cell Rep. 2015. PMID: 26344773 Free PMC article.
211 results