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Fulvene-5 potently inhibits NADPH oxidase 4 and blocks the growth of endothelial tumors in mice.
Bhandarkar SS, Jaconi M, Fried LE, Bonner MY, Lefkove B, Govindarajan B, Perry BN, Parhar R, Mackelfresh J, Sohn A, Stouffs M, Knaus U, Yancopoulos G, Reiss Y, Benest AV, Augustin HG, Arbiser JL. Bhandarkar SS, et al. Among authors: perry bn. J Clin Invest. 2009 Aug;119(8):2359-65. doi: 10.1172/JCI33877. Epub 2009 Jul 13. J Clin Invest. 2009. PMID: 19620773 Free PMC article.
Pharmacologic blockade of angiopoietin-2 is efficacious against model hemangiomas in mice.
Perry BN, Govindarajan B, Bhandarkar SS, Knaus UG, Valo M, Sturk C, Carrillo CO, Sohn A, Cerimele F, Dumont D, Losken A, Williams J, Brown LF, Tan X, Ioffe E, Yancopoulos GD, Arbiser JL. Perry BN, et al. J Invest Dermatol. 2006 Oct;126(10):2316-22. doi: 10.1038/sj.jid.5700413. Epub 2006 Jun 1. J Invest Dermatol. 2006. PMID: 16741507 Free article.
Solenopsin, the alkaloidal component of the fire ant (Solenopsis invicta), is a naturally occurring inhibitor of phosphatidylinositol-3-kinase signaling and angiogenesis.
Arbiser JL, Kau T, Konar M, Narra K, Ramchandran R, Summers SA, Vlahos CJ, Ye K, Perry BN, Matter W, Fischl A, Cook J, Silver PA, Bain J, Cohen P, Whitmire D, Furness S, Govindarajan B, Bowen JP. Arbiser JL, et al. Among authors: perry bn. Blood. 2007 Jan 15;109(2):560-5. doi: 10.1182/blood-2006-06-029934. Epub 2006 Sep 21. Blood. 2007. PMID: 16990598 Free PMC article.
51 results