Trondl R - Search Results

1

Impact of metal coordination on cytotoxicity of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (triapine) and novel insights into terminal dimethylation.

Kowol CR, Trondl R, Heffeter P, Arion VB, Jakupec MA, Roller A, Galanski MS, Berger W, Keppler BK. Kowol CR, et al. Among authors: trondl r. J Med Chem. 2009 Aug 27;52(16):5032-43. doi: 10.1021/jm900528d. J Med Chem. 2009. PMID: 19637923

2

Fluorescence properties and cellular distribution of the investigational anticancer drug triapine (3-aminopyridine-2-carboxaldehyde thiosemicarbazone) and its zinc(II) complex.

Kowol CR, Trondl R, Arion VB, Jakupec MA, Lichtscheidl I, Keppler BK. Kowol CR, et al. Among authors: trondl r. Dalton Trans. 2010 Jan 21;39(3):704-6. doi: 10.1039/b919119b. Epub 2009 Oct 22. Dalton Trans. 2010. PMID: 20066211

3

Mechanisms underlying reductant-induced reactive oxygen species formation by anticancer copper(II) compounds.

Kowol CR, Heffeter P, Miklos W, Gille L, Trondl R, Cappellacci L, Berger W, Keppler BK. Kowol CR, et al. Among authors: trondl r. J Biol Inorg Chem. 2012 Mar;17(3):409-23. doi: 10.1007/s00775-011-0864-x. Epub 2011 Dec 22. J Biol Inorg Chem. 2012. PMID: 22189939 Free PMC article.

4

L- and D-proline thiosemicarbazone conjugates: coordination behavior in solution and the effect of copper(II) coordination on their antiproliferative activity.

Milunovic MN, Enyedy É, Nagy NV, Kiss T, Trondl R, Jakupec MA, Keppler BK, Krachler R, Novitchi G, Arion VB. Milunovic MN, et al. Among authors: trondl r. Inorg Chem. 2012 Sep 3;51(17):9309-21. doi: 10.1021/ic300967j. Epub 2012 Aug 13. Inorg Chem. 2012. PMID: 22889304

5

Targeting the DNA-topoisomerase complex in a double-strike approach with a topoisomerase inhibiting moiety and covalent DNA binder.

Kurzwernhart A, Kandioller W, Bartel C, Bächler S, Trondl R, Mühlgassner G, Jakupec MA, Arion VB, Marko D, Keppler BK, Hartinger CG. Kurzwernhart A, et al. Among authors: trondl r. Chem Commun (Camb). 2012 May 18;48(40):4839-41. doi: 10.1039/c2cc31040f. Epub 2012 Apr 12. Chem Commun (Camb). 2012. PMID: 22498692

6

Copper(II) complexes with highly water-soluble L- and D-proline-thiosemicarbazone conjugates as potential inhibitors of Topoisomerase IIα.

Bacher F, Enyedy É, Nagy NV, Rockenbauer A, Bognár GM, Trondl R, Novak MS, Klapproth E, Kiss T, Arion VB. Bacher F, et al. Among authors: trondl r. Inorg Chem. 2013 Aug 5;52(15):8895-908. doi: 10.1021/ic401079w. Epub 2013 Jul 5. Inorg Chem. 2013. PMID: 23829568

7

Triapine and a more potent dimethyl derivative induce endoplasmic reticulum stress in cancer cells.

Trondl R, Flocke LS, Kowol CR, Heffeter P, Jungwirth U, Mair GE, Steinborn R, Enyedy ÉA, Jakupec MA, Berger W, Keppler BK. Trondl R, et al. Mol Pharmacol. 2014 Mar;85(3):451-9. doi: 10.1124/mol.113.090605. Epub 2013 Dec 30. Mol Pharmacol. 2014. PMID: 24378333

8

Three-dimensional and co-culture models for preclinical evaluation of metal-based anticancer drugs.

Schreiber-Brynzak E, Klapproth E, Unger C, Lichtscheidl-Schultz I, Göschl S, Schweighofer S, Trondl R, Dolznig H, Jakupec MA, Keppler BK. Schreiber-Brynzak E, et al. Among authors: trondl r. Invest New Drugs. 2015 Aug;33(4):835-47. doi: 10.1007/s10637-015-0260-4. Epub 2015 Jun 21. Invest New Drugs. 2015. PMID: 26091914

9

Molecular mode of action of NKP-1339 - a clinically investigated ruthenium-based drug - involves ER- and ROS-related effects in colon carcinoma cell lines.

Flocke LS, Trondl R, Jakupec MA, Keppler BK. Flocke LS, et al. Among authors: trondl r. Invest New Drugs. 2016 Jun;34(3):261-8. doi: 10.1007/s10637-016-0337-8. Epub 2016 Mar 18. Invest New Drugs. 2016. PMID: 26988975 Free PMC article.

10

Comparative solution equilibrium studies of anticancer gallium(III) complexes of 8-hydroxyquinoline and hydroxy(thio)pyrone ligands.

Enyedy ÉA, Dömötör O, Varga E, Kiss T, Trondl R, Hartinger CG, Keppler BK. Enyedy ÉA, et al. Among authors: trondl r. J Inorg Biochem. 2012 Dec;117:189-97. doi: 10.1016/j.jinorgbio.2012.08.005. Epub 2012 Aug 24. J Inorg Biochem. 2012. PMID: 23089600

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