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MicroRNAs and histone deacetylase inhibition-mediated protection against inflammatory β-cell damage.
Lindeløv Vestergaard A, Heiner Bang-Berthelsen C, Fløyel T, Lucien Stahl J, Christen L, Taheri Sotudeh F, de Hemmer Horskjær P, Stensgaard Frederiksen K, Greek Kofod F, Bruun C, Adrian Berchtold L, Størling J, Regazzi R, Kaur S, Pociot F, Mandrup-Poulsen T. Lindeløv Vestergaard A, et al. Among authors: bruun c. PLoS One. 2018 Sep 27;13(9):e0203713. doi: 10.1371/journal.pone.0203713. eCollection 2018. PLoS One. 2018. PMID: 30260972 Free PMC article.
Bone morphogenetic protein 4 inhibits insulin secretion from rodent beta cells through regulation of calbindin1 expression and reduced voltage-dependent calcium currents.
Christensen GL, Jacobsen ML, Wendt A, Mollet IG, Friberg J, Frederiksen KS, Meyer M, Bruun C, Eliasson L, Billestrup N. Christensen GL, et al. Among authors: bruun c. Diabetologia. 2015 Jun;58(6):1282-90. doi: 10.1007/s00125-015-3568-x. Epub 2015 Apr 2. Diabetologia. 2015. PMID: 25828920
Proliferation of sorted human and rat beta cells.
Parnaud G, Bosco D, Berney T, Pattou F, Kerr-Conte J, Donath MY, Bruun C, Mandrup-Poulsen T, Billestrup N, Halban PA. Parnaud G, et al. Among authors: bruun c. Diabetologia. 2008 Jan;51(1):91-100. doi: 10.1007/s00125-007-0855-1. Epub 2007 Nov 10. Diabetologia. 2008. PMID: 17994216
Partial promoter substitutions generating transcriptional sentinels of diverse signaling pathways in embryonic stem cells and mice.
Serup P, Gustavsen C, Klein T, Potter LA, Lin R, Mullapudi N, Wandzioch E, Hines A, Davis A, Bruun C, Engberg N, Petersen DR, Peterslund JM, Macdonald RJ, Grapin-Botton A, Magnuson MA, Zaret KS. Serup P, et al. Among authors: bruun c. Dis Model Mech. 2012 Nov;5(6):956-66. doi: 10.1242/dmm.009696. Epub 2012 Aug 10. Dis Model Mech. 2012. PMID: 22888097 Free PMC article.
The EndoC-βH1 cell line is a valid model of human beta cells and applicable for screenings to identify novel drug target candidates.
Tsonkova VG, Sand FW, Wolf XA, Grunnet LG, Kirstine Ringgaard A, Ingvorsen C, Winkel L, Kalisz M, Dalgaard K, Bruun C, Fels JJ, Helgstrand C, Hastrup S, Öberg FK, Vernet E, Sandrini MPB, Shaw AC, Jessen C, Grønborg M, Hald J, Willenbrock H, Madsen D, Wernersson R, Hansson L, Jensen JN, Plesner A, Alanentalo T, Petersen MBK, Grapin-Botton A, Honoré C, Ahnfelt-Rønne J, Hecksher-Sørensen J, Ravassard P, Madsen OD, Rescan C, Frogne T. Tsonkova VG, et al. Among authors: bruun c. Mol Metab. 2018 Feb;8:144-157. doi: 10.1016/j.molmet.2017.12.007. Epub 2017 Dec 19. Mol Metab. 2018. PMID: 29307512 Free PMC article.
Analysis artefacts of the INS-IGF2 fusion transcript.
Wernersson R, Frogne T, Rescan C, Hansson L, Bruun C, Grønborg M, Jensen JN, Madsen OD. Wernersson R, et al. Among authors: bruun c. BMC Mol Biol. 2015 Jul 29;16:13. doi: 10.1186/s12867-015-0042-8. BMC Mol Biol. 2015. PMID: 26220792 Free PMC article.
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