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Page 1
Suppressor of cytokine signalling (SOCS)-3 protects beta cells against IL-1beta-mediated toxicity through inhibition of multiple nuclear factor-kappaB-regulated proapoptotic pathways.
Karlsen AE, Heding PE, Frobøse H, Rønn SG, Kruhøffer M, Orntoft TF, Darville M, Eizirik DL, Pociot F, Nerup J, Mandrup-Poulsen T, Billestrup N. Karlsen AE, et al. Among authors: heding pe. Diabetologia. 2004 Nov;47(11):1998-2011. doi: 10.1007/s00125-004-1568-3. Epub 2004 Dec 2. Diabetologia. 2004. PMID: 15578154
Type 1 database mellitus: an inflammatory disease of the islet.
Bergholdt R, Heding P, Nielsen K, Nolsøe R, Sparre T, Størling J, Nerup J, Pociot F, Mandrup-Poulsen T. Bergholdt R, et al. Adv Exp Med Biol. 2004;552:129-53. Adv Exp Med Biol. 2004. PMID: 15622962 Review. No abstract available.
Immune-mediated beta-cell destruction in vitro and in vivo-A pivotal role for galectin-3.
Karlsen AE, Størling ZM, Sparre T, Larsen MR, Mahmood A, Størling J, Roepstorff P, Wrzesinski K, Larsen PM, Fey S, Nielsen K, Heding P, Ricordi C, Johannesen J, Kristiansen OP, Christensen UB, Kockum I, Luthman H, Nerup J, Pociot F. Karlsen AE, et al. Biochem Biophys Res Commun. 2006 May 26;344(1):406-15. doi: 10.1016/j.bbrc.2006.03.105. Epub 2006 Mar 29. Biochem Biophys Res Commun. 2006. PMID: 16600178