Pinto JR - Search Results

1

Functional effects of a restrictive-cardiomyopathy-linked cardiac troponin I mutation (R145W) in transgenic mice.

Wen Y, Xu Y, Wang Y, Pinto JR, Potter JD, Kerrick WG. Wen Y, et al. Among authors: pinto jr. J Mol Biol. 2009 Oct 9;392(5):1158-67. doi: 10.1016/j.jmb.2009.07.080. Epub 2009 Aug 3. J Mol Biol. 2009. PMID: 19651143 Free PMC article.

2

A troponin T mutation that causes infantile restrictive cardiomyopathy increases Ca2+ sensitivity of force development and impairs the inhibitory properties of troponin.

Pinto JR, Parvatiyar MS, Jones MA, Liang J, Potter JD. Pinto JR, et al. J Biol Chem. 2008 Jan 25;283(4):2156-66. doi: 10.1074/jbc.M707066200. Epub 2007 Nov 21. J Biol Chem. 2008. PMID: 18032382 Free article.

3

Functional consequences of the human cardiac troponin I hypertrophic cardiomyopathy mutation R145G in transgenic mice.

Wen Y, Pinto JR, Gomes AV, Xu Y, Wang Y, Wang Y, Potter JD, Kerrick WG. Wen Y, et al. Among authors: pinto jr. J Biol Chem. 2008 Jul 18;283(29):20484-94. doi: 10.1074/jbc.M801661200. Epub 2008 Apr 22. J Biol Chem. 2008. PMID: 18430738 Free PMC article.

4

Molecular and functional characterization of novel hypertrophic cardiomyopathy susceptibility mutations in TNNC1-encoded troponin C.

Landstrom AP, Parvatiyar MS, Pinto JR, Marquardt ML, Bos JM, Tester DJ, Ommen SR, Potter JD, Ackerman MJ. Landstrom AP, et al. Among authors: pinto jr. J Mol Cell Cardiol. 2008 Aug;45(2):281-8. doi: 10.1016/j.yjmcc.2008.05.003. Epub 2008 May 11. J Mol Cell Cardiol. 2008. PMID: 18572189 Free PMC article.

5

Myofilament Ca2+ sensitization causes susceptibility to cardiac arrhythmia in mice.

Baudenbacher F, Schober T, Pinto JR, Sidorov VY, Hilliard F, Solaro RJ, Potter JD, Knollmann BC. Baudenbacher F, et al. Among authors: pinto jr. J Clin Invest. 2008 Dec;118(12):3893-903. doi: 10.1172/JCI36642. Epub 2008 Nov 20. J Clin Invest. 2008. PMID: 19033660 Free PMC article.

6

A functional and structural study of troponin C mutations related to hypertrophic cardiomyopathy.

Pinto JR, Parvatiyar MS, Jones MA, Liang J, Ackerman MJ, Potter JD. Pinto JR, et al. J Biol Chem. 2009 Jul 10;284(28):19090-100. doi: 10.1074/jbc.M109.007021. Epub 2009 May 12. J Biol Chem. 2009. PMID: 19439414 Free PMC article.

7

Mutations in Troponin that cause HCM, DCM AND RCM: what can we learn about thin filament function?

Willott RH, Gomes AV, Chang AN, Parvatiyar MS, Pinto JR, Potter JD. Willott RH, et al. Among authors: pinto jr. J Mol Cell Cardiol. 2010 May;48(5):882-92. doi: 10.1016/j.yjmcc.2009.10.031. Epub 2009 Nov 12. J Mol Cell Cardiol. 2010. PMID: 19914256 Review.

8

Clinical and functional characterization of TNNT2 mutations identified in patients with dilated cardiomyopathy.

Hershberger RE, Pinto JR, Parks SB, Kushner JD, Li D, Ludwigsen S, Cowan J, Morales A, Parvatiyar MS, Potter JD. Hershberger RE, et al. Among authors: pinto jr. Circ Cardiovasc Genet. 2009 Aug;2(4):306-13. doi: 10.1161/CIRCGENETICS.108.846733. Epub 2009 May 15. Circ Cardiovasc Genet. 2009. PMID: 20031601 Free PMC article.

9

A dilated cardiomyopathy troponin C mutation lowers contractile force by reducing strong myosin-actin binding.

Dweck D, Reynaldo DP, Pinto JR, Potter JD. Dweck D, et al. Among authors: pinto jr. J Biol Chem. 2010 Jun 4;285(23):17371-9. doi: 10.1074/jbc.M109.064105. Epub 2010 Apr 6. J Biol Chem. 2010. PMID: 20371872 Free PMC article.

10

Predicting cardiomyopathic phenotypes by altering Ca2+ affinity of cardiac troponin C.

Parvatiyar MS, Pinto JR, Liang J, Potter JD. Parvatiyar MS, et al. Among authors: pinto jr. J Biol Chem. 2010 Sep 3;285(36):27785-97. doi: 10.1074/jbc.M110.112326. Epub 2010 Jun 21. J Biol Chem. 2010. PMID: 20566645 Free PMC article.

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