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CDK2 is dispensable for adult hippocampal neurogenesis.
Vandenbosch R, Borgs L, Beukelaers P, Foidart A, Nguyen L, Moonen G, Berthet C, Kaldis P, Gallo V, Belachew S, Malgrange B. Vandenbosch R, et al. Among authors: berthet c. Cell Cycle. 2007 Dec 15;6(24):3065-9. doi: 10.4161/cc.6.24.5048. Epub 2007 Sep 14. Cell Cycle. 2007. PMID: 18073538
Cdk2 knockout mice are viable.
Berthet C, Aleem E, Coppola V, Tessarollo L, Kaldis P. Berthet C, et al. Curr Biol. 2003 Oct 14;13(20):1775-85. doi: 10.1016/j.cub.2003.09.024. Curr Biol. 2003. PMID: 14561402 Free article.
Hematopoiesis and thymic apoptosis are not affected by the loss of Cdk2.
Berthet C, Rodriguez-Galan MC, Hodge DL, Gooya J, Pascal V, Young HA, Keller J, Bosselut R, Kaldis P. Berthet C, et al. Mol Cell Biol. 2007 Jul;27(14):5079-89. doi: 10.1128/MCB.00029-07. Epub 2007 May 7. Mol Cell Biol. 2007. PMID: 17485443 Free PMC article.
62 results