Breitinger HG - Search Results

1

Novel regulatory site within the TM3-4 loop of human recombinant alpha3 glycine receptors determines channel gating and domain structure.

Breitinger HG, Villmann C, Melzer N, Rennert J, Breitinger U, Schwarzinger S, Becker CM. Breitinger HG, et al. Among authors: breitinger u. J Biol Chem. 2009 Oct 16;284(42):28624-33. doi: 10.1074/jbc.M109.043174. Epub 2009 Aug 6. J Biol Chem. 2009. PMID: 19661067 Free PMC article.

2

The inhibitory glycine receptor: prospects for a therapeutic orphan?

Breitinger HG, Becker CM. Breitinger HG, et al. Curr Pharm Des. 1998 Aug;4(4):315-34. Curr Pharm Des. 1998. PMID: 10197046 Review.

3

Opposing effects of molecular volume and charge at the hyperekplexia site alpha 1(P250) govern glycine receptor activation and desensitization.

Breitinger HG, Villmann C, Becker K, Becker CM. Breitinger HG, et al. J Biol Chem. 2001 Aug 10;276(32):29657-63. doi: 10.1074/jbc.M100446200. Epub 2001 Jun 6. J Biol Chem. 2001. PMID: 11395484 Free article.

4

Fast kinetic analysis of ligand-gated ion channels.

Breitinger HG. Breitinger HG. Neuroscientist. 2001 Apr;7(2):95-103. doi: 10.1177/107385840100700204. Neuroscientist. 2001. PMID: 11496930 Review.

5

Hydroxylated residues influence desensitization behaviour of recombinant alpha3 glycine receptor channels.

Breitinger HG, Villmann C, Rennert J, Ballhausen D, Becker CM. Breitinger HG, et al. J Neurochem. 2002 Oct;83(1):30-6. doi: 10.1046/j.1471-4159.2002.01109.x. J Neurochem. 2002. PMID: 12358726 Free article.

6

Statistical coassembly of glycine receptor alpha1 wildtype and the hyperekplexia mutant alpha1(P250T) in HEK 293 cells: impaired channel function is not dominant in the recombinant system.

Breitinger HG, Becker CM. Breitinger HG, et al. Neurosci Lett. 2002 Oct 4;331(1):21-4. doi: 10.1016/s0304-3940(02)00773-5. Neurosci Lett. 2002. PMID: 12359314

7

Kainate-binding proteins are rendered functional ion channels upon transplantation of two short pore-flanking domains from a kainate receptor.

Strutz N, Villmann C, Breitinger HG, Werner M, Wenthold RJ, Kizelsztein P, Teichberg VI, Hollmann M. Strutz N, et al. Among authors: breitinger hg. J Biol Chem. 2002 Dec 13;277(50):48035-42. doi: 10.1074/jbc.M209647200. Epub 2002 Oct 5. J Biol Chem. 2002. PMID: 12370171 Free article.

8

The inhibitory glycine receptor-simple views of a complicated channel.

Breitinger HG, Becker CM. Breitinger HG, et al. Chembiochem. 2002 Nov 4;3(11):1042-52. doi: 10.1002/1439-7633(20021104)3:11<1042::AID-CBIC1042>3.0.CO;2-7. Chembiochem. 2002. PMID: 12404628 Review.

9

Conserved high affinity ligand binding and membrane association in the native and refolded extracellular domain of the human glycine receptor alpha1-subunit.

Breitinger U, Breitinger HG, Bauer F, Fahmy K, Glockenhammer D, Becker CM. Breitinger U, et al. Among authors: breitinger hg. J Biol Chem. 2004 Jan 16;279(3):1627-36. doi: 10.1074/jbc.M303811200. Epub 2003 Oct 30. J Biol Chem. 2004. PMID: 14593111 Free article.

10

Molecular dynamics simulation links conformation of a pore-flanking region to hyperekplexia-related dysfunction of the inhibitory glycine receptor.

Breitinger HG, Lanig H, Vohwinkel C, Grewer C, Breitinger U, Clark T, Becker CM. Breitinger HG, et al. Among authors: breitinger u. Chem Biol. 2004 Oct;11(10):1339-50. doi: 10.1016/j.chembiol.2004.07.008. Chem Biol. 2004. PMID: 15489161

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