Cance WG - Search Results

1

Targeting of the protein interaction site between FAK and IGF-1R.

Zheng D, Kurenova E, Ucar D, Golubovskaya V, Magis A, Ostrov D, Cance WG, Hochwald SN. Zheng D, et al. Among authors: cance wg. Biochem Biophys Res Commun. 2009 Oct 16;388(2):301-5. doi: 10.1016/j.bbrc.2009.07.156. Epub 2009 Aug 5. Biochem Biophys Res Commun. 2009. PMID: 19664602 Free PMC article.

2

Vascular endothelial growth factor receptor-3 and focal adhesion kinase bind and suppress apoptosis in breast cancer cells.

Garces CA, Kurenova EV, Golubovskaya VM, Cance WG. Garces CA, et al. Among authors: cance wg. Cancer Res. 2006 Feb 1;66(3):1446-54. doi: 10.1158/0008-5472.CAN-05-1661. Cancer Res. 2006. PMID: 16452200

3

Focal adhesion kinase and p53 signaling in cancer cells.

Golubovskaya VM, Cance WG. Golubovskaya VM, et al. Among authors: cance wg. Int Rev Cytol. 2007;263:103-53. doi: 10.1016/S0074-7696(07)63003-4. Int Rev Cytol. 2007. PMID: 17725966 Review.

4

The 7-amino-acid site in the proline-rich region of the N-terminal domain of p53 is involved in the interaction with FAK and is critical for p53 functioning.

Golubovskaya VM, Finch R, Zheng M, Kurenova EV, Cance WG. Golubovskaya VM, et al. Among authors: cance wg. Biochem J. 2008 Apr 1;411(1):151-60. doi: 10.1042/BJ20071657. Biochem J. 2008. PMID: 18215142

5

FAK and IGF-IR interact to provide survival signals in human pancreatic adenocarcinoma cells.

Liu W, Bloom DA, Cance WG, Kurenova EV, Golubovskaya VM, Hochwald SN. Liu W, et al. Among authors: cance wg. Carcinogenesis. 2008 Jun;29(6):1096-107. doi: 10.1093/carcin/bgn026. Epub 2008 Feb 7. Carcinogenesis. 2008. PMID: 18263593 Free PMC article.

6

Focal adhesion kinase versus p53: apoptosis or survival?

Cance WG, Golubovskaya VM. Cance WG, et al. Sci Signal. 2008 May 20;1(20):pe22. doi: 10.1126/stke.120pe22. Sci Signal. 2008. PMID: 18493017 Free PMC article. Review.

7

Crystallization of the focal adhesion kinase targeting (FAT) domain in a primitive orthorhombic space group.

Magis AT, Bailey KM, Kurenova EV, Hernández Prada JA, Cance WG, Ostrov DA. Magis AT, et al. Among authors: cance wg. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008 Jun 1;64(Pt 6):564-6. doi: 10.1107/S1744309108011421. Epub 2008 May 30. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008. PMID: 18540077 Free PMC article.

8

A small molecule inhibitor, 1,2,4,5-benzenetetraamine tetrahydrochloride, targeting the y397 site of focal adhesion kinase decreases tumor growth.

Golubovskaya VM, Nyberg C, Zheng M, Kweh F, Magis A, Ostrov D, Cance WG. Golubovskaya VM, et al. Among authors: cance wg. J Med Chem. 2008 Dec 11;51(23):7405-16. doi: 10.1021/jm800483v. J Med Chem. 2008. PMID: 18989950 Free PMC article.

9

A novel small molecule inhibitor of FAK decreases growth of human pancreatic cancer.

Hochwald SN, Nyberg C, Zheng M, Zheng D, Wood C, Massoll NA, Magis A, Ostrov D, Cance WG, Golubovskaya VM. Hochwald SN, et al. Among authors: cance wg. Cell Cycle. 2009 Aug;8(15):2435-43. doi: 10.4161/cc.8.15.9145. Epub 2009 Aug 1. Cell Cycle. 2009. PMID: 19571674 Free PMC article.

10

A novel strategy to inhibit FAK and IGF-1R decreases growth of pancreatic cancer xenografts.

Zheng D, Golubovskaya V, Kurenova E, Wood C, Massoll NA, Ostrov D, Cance WG, Hochwald SN. Zheng D, et al. Among authors: cance wg. Mol Carcinog. 2010 Feb;49(2):200-9. doi: 10.1002/mc.20590. Mol Carcinog. 2010. PMID: 19885860 Free PMC article.

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