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The death receptor CD95 activates adult neural stem cells for working memory formation and brain repair.
Corsini NS, Sancho-Martinez I, Laudenklos S, Glagow D, Kumar S, Letellier E, Koch P, Teodorczyk M, Kleber S, Klussmann S, Wiestler B, Brüstle O, Mueller W, Gieffers C, Hill O, Thiemann M, Seedorf M, Gretz N, Sprengel R, Celikel T, Martin-Villalba A. Corsini NS, et al. Among authors: gieffers c. Cell Stem Cell. 2009 Aug 7;5(2):178-90. doi: 10.1016/j.stem.2009.05.004. Cell Stem Cell. 2009. PMID: 19664992 Free article.
Yes and PI3K bind CD95 to signal invasion of glioblastoma.
Kleber S, Sancho-Martinez I, Wiestler B, Beisel A, Gieffers C, Hill O, Thiemann M, Mueller W, Sykora J, Kuhn A, Schreglmann N, Letellier E, Zuliani C, Klussmann S, Teodorczyk M, Gröne HJ, Ganten TM, Sültmann H, Tüttenberg J, von Deimling A, Regnier-Vigouroux A, Herold-Mende C, Martin-Villalba A. Kleber S, et al. Among authors: gieffers c. Cancer Cell. 2008 Mar;13(3):235-48. doi: 10.1016/j.ccr.2008.02.003. Cancer Cell. 2008. PMID: 18328427 Free article.
CD95 promotes metastatic spread via Sck in pancreatic ductal adenocarcinoma.
Teodorczyk M, Kleber S, Wollny D, Sefrin JP, Aykut B, Mateos A, Herhaus P, Sancho-Martinez I, Hill O, Gieffers C, Sykora J, Weichert W, Eisen C, Trumpp A, Sprick MR, Bergmann F, Welsch T, Martin-Villalba A. Teodorczyk M, et al. Among authors: gieffers c. Cell Death Differ. 2015 Jul;22(7):1192-202. doi: 10.1038/cdd.2014.217. Epub 2015 Jan 23. Cell Death Differ. 2015. PMID: 25613377 Free PMC article.
Concepts for agonistic targeting of CD40 in immuno-oncology.
Richards DM, Sefrin JP, Gieffers C, Hill O, Merz C. Richards DM, et al. Among authors: gieffers c. Hum Vaccin Immunother. 2020;16(2):377-387. doi: 10.1080/21645515.2019.1653744. Epub 2019 Sep 5. Hum Vaccin Immunother. 2020. PMID: 31403344 Free PMC article. Review.
33 results