Watterson S - Search Results

1

Le Novère N, Hucka M, Mi H, Moodie S, Schreiber F, Sorokin A, Demir E, Wegner K, Aladjem MI, Wimalaratne SM, Bergman FT, Gauges R, Ghazal P, Kawaji H, Li L, Matsuoka Y, Villéger A, Boyd SE, Calzone L, Courtot M, Dogrusoz U, Freeman TC, Funahashi A, Ghosh S, Jouraku A, Kim S, Kolpakov F, Luna A, Sahle S, Schmidt E, Watterson S, Wu G, Goryanin I, Kell DB, Sander C, Sauro H, Snoep JL, Kohn K, Kitano H. Le Novère N, et al. Among authors: watterson s. Nat Biotechnol. 2009 Aug;27(8):735-41. doi: 10.1038/nbt.1558. Epub 2009 Aug 7. Nat Biotechnol. 2009. PMID: 19668183 Free article.

2

Logic models of pathway biology.

Watterson S, Marshall S, Ghazal P. Watterson S, et al. Drug Discov Today. 2008 May;13(9-10):447-56. doi: 10.1016/j.drudis.2008.03.019. Epub 2008 Apr 23. Drug Discov Today. 2008. PMID: 18468563 Review.

3

Use of logic theory in understanding regulatory pathway signaling in response to infection.

Watterson S, Ghazal P. Watterson S, et al. Future Microbiol. 2010 Feb;5(2):163-76. doi: 10.2217/fmb.10.8. Future Microbiol. 2010. PMID: 20143942 Free article. Review.

4

A comprehensive machine-readable view of the mammalian cholesterol biosynthesis pathway.

Mazein A, Watterson S, Hsieh WY, Griffiths WJ, Ghazal P. Mazein A, et al. Among authors: watterson s. Biochem Pharmacol. 2013 Jul 1;86(1):56-66. doi: 10.1016/j.bcp.2013.03.021. Epub 2013 Apr 10. Biochem Pharmacol. 2013. PMID: 23583456 Free PMC article.

5

Inferring Boolean networks with perturbation from sparse gene expression data: a general model applied to the interferon regulatory network.

Yu L, Watterson S, Marshall S, Ghazal P. Yu L, et al. Among authors: watterson s. Mol Biosyst. 2008 Oct;4(10):1024-30. doi: 10.1039/b804649b. Epub 2008 Aug 26. Mol Biosyst. 2008. PMID: 19082142

6

The in silico macrophage: toward a better understanding of inflammatory disease.

Ghazal P, Watterson S, Robertson K, Kluth DC. Ghazal P, et al. Among authors: watterson s. Genome Med. 2011 Jan 22;3(1):4. doi: 10.1186/gm218. Genome Med. 2011. PMID: 21349141 Free PMC article.

7

Construction of a large scale integrated map of macrophage pathogen recognition and effector systems.

Raza S, McDerment N, Lacaze PA, Robertson K, Watterson S, Chen Y, Chisholm M, Eleftheriadis G, Monk S, O'Sullivan M, Turnbull A, Roy D, Theocharidis A, Ghazal P, Freeman TC. Raza S, et al. Among authors: watterson s. BMC Syst Biol. 2010 May 14;4:63. doi: 10.1186/1752-0509-4-63. BMC Syst Biol. 2010. PMID: 20470404 Free PMC article.

8

Digital clocks: simple Boolean models can quantitatively describe circadian systems.

Akman OE, Watterson S, Parton A, Binns N, Millar AJ, Ghazal P. Akman OE, et al. Among authors: watterson s. J R Soc Interface. 2012 Sep 7;9(74):2365-82. doi: 10.1098/rsif.2012.0080. Epub 2012 Apr 12. J R Soc Interface. 2012. PMID: 22499125 Free PMC article.

9

Rapid proteasomal elimination of 3-hydroxy-3-methylglutaryl-CoA reductase by interferon-γ in primary macrophages requires endogenous 25-hydroxycholesterol synthesis.

Lu H, Talbot S, Robertson KA, Watterson S, Forster T, Roy D, Ghazal P. Lu H, et al. Among authors: watterson s. Steroids. 2015 Jul;99(Pt B):219-29. doi: 10.1016/j.steroids.2015.02.022. Epub 2015 Mar 7. Steroids. 2015. PMID: 25759117 Free PMC article.

10

Is systems pharmacology ready to impact upon therapy development? A study on the cholesterol biosynthesis pathway.

Benson HE, Watterson S, Sharman JL, Mpamhanga CP, Parton A, Southan C, Harmar AJ, Ghazal P. Benson HE, et al. Among authors: watterson s. Br J Pharmacol. 2017 Dec;174(23):4362-4382. doi: 10.1111/bph.14037. Epub 2017 Nov 26. Br J Pharmacol. 2017. PMID: 28910500 Free PMC article.

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