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Presenilin mutations associated with Alzheimer disease cause defective intracellular trafficking of beta-catenin, a component of the presenilin protein complex.
Nishimura M, Yu G, Levesque G, Zhang DM, Ruel L, Chen F, Milman P, Holmes E, Liang Y, Kawarai T, Jo E, Supala A, Rogaeva E, Xu DM, Janus C, Levesque L, Bi Q, Duthie M, Rozmahel R, Mattila K, Lannfelt L, Westaway D, Mount HT, Woodgett J, St George-Hyslop P, et al. Nishimura M, et al. Among authors: mount ht. Nat Med. 1999 Feb;5(2):164-9. doi: 10.1038/5526. Nat Med. 1999. PMID: 9930863
Object recognition memory and BDNF expression are reduced in young TgCRND8 mice.
Francis BM, Kim J, Barakat ME, Fraenkl S, Yücel YH, Peng S, Michalski B, Fahnestock M, McLaurin J, Mount HT. Francis BM, et al. Among authors: mount ht. Neurobiol Aging. 2012 Mar;33(3):555-63. doi: 10.1016/j.neurobiolaging.2010.04.003. Epub 2010 May 5. Neurobiol Aging. 2012. PMID: 20447730 Free PMC article.
63 results