Yang SW - Search Results

1

Discovery of orally active 3-pyridinyl-tropane as a potent nociceptin receptor agonist for the management of cough.

Yang SW, Ho G, Tulshian D, Greenlee WJ, Anthes J, Fernandez X, McLeod RL, Hey JA, Xu X. Yang SW, et al. J Med Chem. 2009 Sep 10;52(17):5323-9. doi: 10.1021/jm9008218. J Med Chem. 2009. PMID: 19678644

2

A new sterol sulfate, Sch 572423, from a marine sponge, Topsentia sp.

Yang SW, Buivich A, Chan TM, Smith M, Lachowicz J, Pomponi SA, Wright AE, Mierzwa R, Patel M, Gullo V, Chu M. Yang SW, et al. Bioorg Med Chem Lett. 2003 May 19;13(10):1791-4. doi: 10.1016/s0960-894x(03)00260-9. Bioorg Med Chem Lett. 2003. PMID: 12729666

3

Structure elucidation of Sch 538415, a novel acyl carrier protein synthase inhibitor from a microorganism.

Chu M, Mierzwa R, Xu L, Yang SW, He L, Patel M, Stafford J, Macinga D, Black T, Chan TM, Gullo V. Chu M, et al. Among authors: yang sw. Bioorg Med Chem Lett. 2003 Nov 3;13(21):3827-9. doi: 10.1016/j.bmcl.2003.07.011. Bioorg Med Chem Lett. 2003. PMID: 14552789

4

Two novel antibiotics, Sch 419558 and Sch 419559, produced by Pseudomonas fluorescens: effect on activity by overexpression of RpoE.

Yang SW, Xu L, Mierzwa R, He L, Terracciano J, Patel M, Gullo V, Black T, Zhao W, Chan TM, Chu M. Yang SW, et al. Bioorg Med Chem. 2004 Jun 15;12(12):3333-8. doi: 10.1016/j.bmc.2004.03.057. Bioorg Med Chem. 2004. PMID: 15158801

5

Structure-activity relationships of 3-substituted N-benzhydryl-nortropane analogs as nociceptin receptor ligands for the treatment of cough.

Yang SW, Ho G, Tulshian D, Greenlee WJ, Fernandez X, McLeod RL, Eckel S, Anthes J. Yang SW, et al. Bioorg Med Chem Lett. 2008 Dec 15;18(24):6340-3. doi: 10.1016/j.bmcl.2008.10.088. Epub 2008 Nov 1. Bioorg Med Chem Lett. 2008. PMID: 18990569

6

Identification of 3-substituted N-benzhydryl-nortropane analogs as nociceptin receptor ligands for the management of cough and anxiety.

Yang SW, Ho G, Tulshian D, Greenlee WJ, Tan Z, Zhang H, Smith-Torhan A, Fawzi A, Anthes J, Lu S, Varty G, Fernandez X, McLeod RL, Hey J. Yang SW, et al. Bioorg Med Chem Lett. 2009 May 1;19(9):2482-6. doi: 10.1016/j.bmcl.2009.03.057. Epub 2009 Mar 18. Bioorg Med Chem Lett. 2009. PMID: 19332374

7

Structure-activity relationships of 2,4-diphenyl-1H-imidazole analogs as CB2 receptor agonists for the treatment of chronic pain.

Yang SW, Smotryski J, Matasi J, Ho G, Tulshian D, Greenlee WJ, Brusa R, Beltramo M, Cox K. Yang SW, et al. Bioorg Med Chem Lett. 2011 Jan 1;21(1):182-5. doi: 10.1016/j.bmcl.2010.11.044. Epub 2010 Nov 11. Bioorg Med Chem Lett. 2011. PMID: 21115245

8

Discovery of orally active pyrazoloquinolines as potent PDE10 inhibitors for the management of schizophrenia.

Yang SW, Smotryski J, McElroy WT, Tan Z, Ho G, Tulshian D, Greenlee WJ, Guzzi M, Zhang X, Mullins D, Xiao L, Hruza A, Chan TM, Rindgen D, Bleickardt C, Hodgson R. Yang SW, et al. Bioorg Med Chem Lett. 2012 Jan 1;22(1):235-9. doi: 10.1016/j.bmcl.2011.11.023. Epub 2011 Nov 16. Bioorg Med Chem Lett. 2012. PMID: 22142545

9

The discovery of potent, selective, and orally active pyrazoloquinolines as PDE10A inhibitors for the treatment of Schizophrenia.

Ho GD, Yang SW, Smotryski J, Bercovici A, Nechuta T, Smith EM, McElroy W, Tan Z, Tulshian D, McKittrick B, Greenlee WJ, Hruza A, Xiao L, Rindgen D, Mullins D, Guzzi M, Zhang X, Bleickardt C, Hodgson R. Ho GD, et al. Among authors: yang sw. Bioorg Med Chem Lett. 2012 Jan 15;22(2):1019-22. doi: 10.1016/j.bmcl.2011.11.127. Epub 2011 Dec 9. Bioorg Med Chem Lett. 2012. PMID: 22222034

10

Pyrazoloquinolines as PDE10A inhibitors: discovery of a tool compound.

McElroy WT, Tan Z, Basu K, Yang SW, Smotryski J, Ho GD, Tulshian D, Greenlee WJ, Mullins D, Guzzi M, Zhang X, Bleickardt C, Hodgson R. McElroy WT, et al. Among authors: yang sw. Bioorg Med Chem Lett. 2012 Feb 1;22(3):1335-9. doi: 10.1016/j.bmcl.2011.12.080. Epub 2011 Dec 21. Bioorg Med Chem Lett. 2012. PMID: 22227212

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