Fushman D - Search Results

1

Structure of the s5a:k48-linked diubiquitin complex and its interactions with rpn13.

Zhang N, Wang Q, Ehlinger A, Randles L, Lary JW, Kang Y, Haririnia A, Storaska AJ, Cole JL, Fushman D, Walters KJ. Zhang N, et al. Among authors: fushman d. Mol Cell. 2009 Aug 14;35(3):280-90. doi: 10.1016/j.molcel.2009.06.010. Mol Cell. 2009. PMID: 19683493 Free PMC article.

2

Solution conformation of Lys63-linked di-ubiquitin chain provides clues to functional diversity of polyubiquitin signaling.

Varadan R, Assfalg M, Haririnia A, Raasi S, Pickart C, Fushman D. Varadan R, et al. Among authors: fushman d. J Biol Chem. 2004 Feb 20;279(8):7055-63. doi: 10.1074/jbc.M309184200. Epub 2003 Nov 25. J Biol Chem. 2004. PMID: 14645257 Free article.

Chem. 267, 16467-16471; Varadan, R., Walker, O., Pickart, C., and Fushman, D. (2002) J. Mol. Biol. 324, 637-647). Consistent with the open conformation of the Lys(63)-linked di-ubiquitin, our binding studies show that both ubiquitin domains in this chain can bind a …

Chem. 267, 16467-16471; Varadan, R., Walker, O., Pickart, C., and Fushman, D. (2002) J. Mol. Biol. 324, 637-647). Consistent w …

3

Structural determinants for selective recognition of a Lys48-linked polyubiquitin chain by a UBA domain.

Varadan R, Assfalg M, Raasi S, Pickart C, Fushman D. Varadan R, et al. Among authors: fushman d. Mol Cell. 2005 Jun 10;18(6):687-98. doi: 10.1016/j.molcel.2005.05.013. Mol Cell. 2005. PMID: 15949443 Free article.

4

Diverse polyubiquitin interaction properties of ubiquitin-associated domains.

Raasi S, Varadan R, Fushman D, Pickart CM. Raasi S, et al. Among authors: fushman d. Nat Struct Mol Biol. 2005 Aug;12(8):708-14. doi: 10.1038/nsmb962. Epub 2005 Jul 10. Nat Struct Mol Biol. 2005. PMID: 16007098

5

Mapping the interactions between Lys48 and Lys63-linked di-ubiquitins and a ubiquitin-interacting motif of S5a.

Haririnia A, D'Onofrio M, Fushman D. Haririnia A, et al. Among authors: d onofrio m, fushman d. J Mol Biol. 2007 May 4;368(3):753-66. doi: 10.1016/j.jmb.2007.02.037. Epub 2007 Feb 22. J Mol Biol. 2007. PMID: 17368669 Free PMC article.

6

Mutations in the hydrophobic core of ubiquitin differentially affect its recognition by receptor proteins.

Haririnia A, Verma R, Purohit N, Twarog MZ, Deshaies RJ, Bolon D, Fushman D. Haririnia A, et al. Among authors: fushman d. J Mol Biol. 2008 Jan 25;375(4):979-96. doi: 10.1016/j.jmb.2007.11.016. Epub 2007 Nov 13. J Mol Biol. 2008. PMID: 18054791 Free PMC article.

7

Evidence for bidentate substrate binding as the basis for the K48 linkage specificity of otubain 1.

Wang T, Yin L, Cooper EM, Lai MY, Dickey S, Pickart CM, Fushman D, Wilkinson KD, Cohen RE, Wolberger C. Wang T, et al. Among authors: fushman d. J Mol Biol. 2009 Mar 6;386(4):1011-23. doi: 10.1016/j.jmb.2008.12.085. Epub 2009 Jan 13. J Mol Biol. 2009. PMID: 19211026 Free PMC article.

8

Avid interactions underlie the Lys63-linked polyubiquitin binding specificities observed for UBA domains.

Sims JJ, Haririnia A, Dickinson BC, Fushman D, Cohen RE. Sims JJ, et al. Among authors: fushman d. Nat Struct Mol Biol. 2009 Aug;16(8):883-9. doi: 10.1038/nsmb.1637. Epub 2009 Jul 20. Nat Struct Mol Biol. 2009. PMID: 19620964 Free PMC article.

9

Together, Rpn10 and Dsk2 can serve as a polyubiquitin chain-length sensor.

Zhang D, Chen T, Ziv I, Rosenzweig R, Matiuhin Y, Bronner V, Glickman MH, Fushman D. Zhang D, et al. Among authors: fushman d. Mol Cell. 2009 Dec 25;36(6):1018-33. doi: 10.1016/j.molcel.2009.11.012. Mol Cell. 2009. PMID: 20064467 Free PMC article.

10

Perturbing the ubiquitin pathway reveals how mitosis is hijacked to denucleate and regulate cell proliferation and differentiation in vivo.

Caceres A, Shang F, Wawrousek E, Liu Q, Avidan O, Cvekl A, Yang Y, Haririnia A, Storaska A, Fushman D, Kuszak J, Dudek E, Smith D, Taylor A. Caceres A, et al. Among authors: fushman d. PLoS One. 2010 Oct 20;5(10):e13331. doi: 10.1371/journal.pone.0013331. PLoS One. 2010. PMID: 20975996 Free PMC article.

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