Bennett JS - Search Results

1

A key role for the integrin alpha2beta1 in experimental and developmental angiogenesis.

San Antonio JD, Zoeller JJ, Habursky K, Turner K, Pimtong W, Burrows M, Choi S, Basra S, Bennett JS, DeGrado WF, Iozzo RV. San Antonio JD, et al. Among authors: bennett js. Am J Pathol. 2009 Sep;175(3):1338-47. doi: 10.2353/ajpath.2009.090234. Epub 2009 Aug 21. Am J Pathol. 2009. PMID: 19700757 Free PMC article.

2

Small molecule inhibitors of integrin alpha2beta1.

Choi S, Vilaire G, Marcinkiewicz C, Winkler JD, Bennett JS, DeGrado WF. Choi S, et al. Among authors: bennett js. J Med Chem. 2007 Nov 1;50(22):5457-62. doi: 10.1021/jm070252b. Epub 2007 Oct 4. J Med Chem. 2007. PMID: 17915848 Free PMC article.

3

Arylamide derivatives as allosteric inhibitors of the integrin alpha2beta1/type I collagen interaction.

Yin H, Gerlach LO, Miller MW, Moore DT, Liu D, Vilaire G, Bennett JS, DeGrado WF. Yin H, et al. Among authors: bennett js. Bioorg Med Chem Lett. 2006 Jul 1;16(13):3380-2. doi: 10.1016/j.bmcl.2006.04.037. Epub 2006 May 5. Bioorg Med Chem Lett. 2006. PMID: 16678410

4

Small-molecule inhibitors of integrin alpha2beta1 that prevent pathological thrombus formation via an allosteric mechanism.

Miller MW, Basra S, Kulp DW, Billings PC, Choi S, Beavers MP, McCarty OJ, Zou Z, Kahn ML, Bennett JS, DeGrado WF. Miller MW, et al. Among authors: bennett js. Proc Natl Acad Sci U S A. 2009 Jan 20;106(3):719-24. doi: 10.1073/pnas.0811622106. Epub 2009 Jan 13. Proc Natl Acad Sci U S A. 2009. PMID: 19141632 Free PMC article.

5

Structural basis for integrin alphaIIbbeta3 clustering.

Li R, Bennett JS, Degrado WF. Li R, et al. Among authors: bennett js. Biochem Soc Trans. 2004 Jun;32(Pt3):412-5. doi: 10.1042/BST0320412. Biochem Soc Trans. 2004. PMID: 15157149 Review.

6

Activation of individual alphaIIbbeta3 integrin molecules by disruption of transmembrane domain interactions in the absence of clustering.

Litvinov RI, Vilaire G, Li W, DeGrado WF, Weisel JW, Bennett JS. Litvinov RI, et al. Among authors: bennett js. Biochemistry. 2006 Apr 18;45(15):4957-64. doi: 10.1021/bi0526581. Biochemistry. 2006. PMID: 16605263

7

Multiple approaches converge on the structure of the integrin alphaIIb/beta3 transmembrane heterodimer.

Metcalf DG, Kulp DW, Bennett JS, DeGrado WF. Metcalf DG, et al. Among authors: bennett js. J Mol Biol. 2009 Oct 2;392(4):1087-101. doi: 10.1016/j.jmb.2009.06.032. Epub 2009 Jun 13. J Mol Biol. 2009. PMID: 19527732 Free PMC article.

8

A push-pull mechanism for regulating integrin function.

Li W, Metcalf DG, Gorelik R, Li R, Mitra N, Nanda V, Law PB, Lear JD, Degrado WF, Bennett JS. Li W, et al. Among authors: bennett js. Proc Natl Acad Sci U S A. 2005 Feb 1;102(5):1424-9. doi: 10.1073/pnas.0409334102. Epub 2005 Jan 25. Proc Natl Acad Sci U S A. 2005. PMID: 15671157 Free PMC article.

9

De novo designed transmembrane peptides activating the α5β1 integrin.

Mravic M, Hu H, Lu Z, Bennett JS, Sanders CR, Orr AW, DeGrado WF. Mravic M, et al. Among authors: bennett js. Protein Eng Des Sel. 2018 May 1;31(5):181-190. doi: 10.1093/protein/gzy014. Protein Eng Des Sel. 2018. PMID: 29992271 Free PMC article.

10

Activation of integrin alphaIIbbeta3 by modulation of transmembrane helix associations.

Li R, Mitra N, Gratkowski H, Vilaire G, Litvinov R, Nagasami C, Weisel JW, Lear JD, DeGrado WF, Bennett JS. Li R, et al. Among authors: bennett js. Science. 2003 May 2;300(5620):795-8. doi: 10.1126/science.1079441. Science. 2003. PMID: 12730600

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