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A small molecule that blocks fat synthesis by inhibiting the activation of SREBP.
Kamisuki S, Mao Q, Abu-Elheiga L, Gu Z, Kugimiya A, Kwon Y, Shinohara T, Kawazoe Y, Sato S, Asakura K, Choo HY, Sakai J, Wakil SJ, Uesugi M. Kamisuki S, et al. Among authors: sakai j. Chem Biol. 2009 Aug 28;16(8):882-92. doi: 10.1016/j.chembiol.2009.07.007. Chem Biol. 2009. PMID: 19716478 Free article.
[SREBP controls cholesterol homeostasis].
Sato R, Sakai J. Sato R, et al. Among authors: sakai j. Seikagaku. 2004 Jun;76(6):503-8. Seikagaku. 2004. PMID: 15287495 Review. Japanese. No abstract available.
SOX6 attenuates glucose-stimulated insulin secretion by repressing PDX1 transcriptional activity and is down-regulated in hyperinsulinemic obese mice.
Iguchi H, Ikeda Y, Okamura M, Tanaka T, Urashima Y, Ohguchi H, Takayasu S, Kojima N, Iwasaki S, Ohashi R, Jiang S, Hasegawa G, Ioka RX, Magoori K, Sumi K, Maejima T, Uchida A, Naito M, Osborne TF, Yanagisawa M, Yamamoto TT, Kodama T, Sakai J. Iguchi H, et al. Among authors: sakai j. J Biol Chem. 2005 Nov 11;280(45):37669-80. doi: 10.1074/jbc.M505392200. Epub 2005 Sep 7. J Biol Chem. 2005. PMID: 16148004 Free article.
Sterol-mediated regulation of human lipin 1 gene expression in hepatoblastoma cells.
Ishimoto K, Nakamura H, Tachibana K, Yamasaki D, Ota A, Hirano KI, Tanaka T, Hamakubo T, Sakai J, Kodama T, Doi T. Ishimoto K, et al. Among authors: sakai j. J Biol Chem. 2009 Aug 14;284(33):22195-22205. doi: 10.1074/jbc.M109.028753. Epub 2009 Jun 24. J Biol Chem. 2009. PMID: 19553673 Free PMC article.
620 results