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Filaggrin deficiency confers a paracellular barrier abnormality that reduces inflammatory thresholds to irritants and haptens.
Scharschmidt TC, Man MQ, Hatano Y, Crumrine D, Gunathilake R, Sundberg JP, Silva KA, Mauro TM, Hupe M, Cho S, Wu Y, Celli A, Schmuth M, Feingold KR, Elias PM. Scharschmidt TC, et al. Among authors: feingold kr. J Allergy Clin Immunol. 2009 Sep;124(3):496-506, 506.e1-6. doi: 10.1016/j.jaci.2009.06.046. J Allergy Clin Immunol. 2009. PMID: 19733297 Free PMC article.
Lamellar body secretory response to barrier disruption.
Menon GK, Feingold KR, Elias PM. Menon GK, et al. Among authors: feingold kr. J Invest Dermatol. 1992 Mar;98(3):279-89. doi: 10.1111/1523-1747.ep12497866. J Invest Dermatol. 1992. PMID: 1545137 Free article.
484 results