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Page 1
Tumor suppression by ARF: gatekeeper and caretaker.
Dominguez-Brauer C, Brauer PM, Chen YJ, Pimkina J, Raychaudhuri P. Dominguez-Brauer C, et al. Cell Cycle. 2010 Jan 1;9(1):86-9. doi: 10.4161/cc.9.1.10350. Cell Cycle. 2010. PMID: 20016279 Review.
Retraction for Roy et al., "DDB2, an Essential Mediator of Premature Senescence".
Roy N, Stoyanova T, Dominguez-Brauer C, Park HJ, Bagchi S, Raychaudhuri P. Roy N, et al. Among authors: dominguez brauer c. Mol Cell Biol. 2017 May 16;37(11):e00135-17. doi: 10.1128/MCB.00135-17. Print 2017 Jun 1. Mol Cell Biol. 2017. PMID: 28512213 Free PMC article. No abstract available.
The ARF tumor suppressor can promote the progression of some tumors.
Humbey O, Pimkina J, Zilfou JT, Jarnik M, Dominguez-Brauer C, Burgess DJ, Eischen CM, Murphy ME. Humbey O, et al. Cancer Res. 2008 Dec 1;68(23):9608-13. doi: 10.1158/0008-5472.CAN-08-2263. Cancer Res. 2008. PMID: 19047137 Free PMC article.
Modeling altered T-cell development with induced pluripotent stem cells from patients with RAG1-dependent immune deficiencies.
Brauer PM, Pessach IM, Clarke E, Rowe JH, Ott de Bruin L, Lee YN, Dominguez-Brauer C, Comeau AM, Awong G, Felgentreff K, Zhang YH, Bredemeyer A, Al-Herz W, Du L, Ververs F, Kennedy M, Giliani S, Keller G, Sleckman BP, Schatz DG, Bushman FD, Notarangelo LD, Zúñiga-Pflücker JC. Brauer PM, et al. Among authors: dominguez brauer c. Blood. 2016 Aug 11;128(6):783-93. doi: 10.1182/blood-2015-10-676304. Epub 2016 Jun 14. Blood. 2016. PMID: 27301863 Free PMC article.
Mule Regulates the Intestinal Stem Cell Niche via the Wnt Pathway and Targets EphB3 for Proteasomal and Lysosomal Degradation.
Dominguez-Brauer C, Hao Z, Elia AJ, Fortin JM, Nechanitzky R, Brauer PM, Sheng Y, Mana MD, Chio IIC, Haight J, Pollett A, Cairns R, Tworzyanski L, Inoue S, Reardon C, Marques A, Silvester J, Cox MA, Wakeham A, Yilmaz OH, Sabatini DM, van Es JH, Clevers H, Sato T, Mak TW. Dominguez-Brauer C, et al. Cell Stem Cell. 2016 Aug 4;19(2):205-216. doi: 10.1016/j.stem.2016.04.002. Epub 2016 May 12. Cell Stem Cell. 2016. PMID: 27184401 Free PMC article.
Mule/Huwe1/Arf-BP1 suppresses Ras-driven tumorigenesis by preventing c-Myc/Miz1-mediated down-regulation of p21 and p15.
Inoue S, Hao Z, Elia AJ, Cescon D, Zhou L, Silvester J, Snow B, Harris IS, Sasaki M, Li WY, Itsumi M, Yamamoto K, Ueda T, Dominguez-Brauer C, Gorrini C, Chio II, Haight J, You-Ten A, McCracken S, Wakeham A, Ghazarian D, Penn LJ, Melino G, Mak TW. Inoue S, et al. Among authors: dominguez brauer c. Genes Dev. 2013 May 15;27(10):1101-14. doi: 10.1101/gad.214577.113. Genes Dev. 2013. PMID: 23699408 Free PMC article.
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