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Interleukin-6 as a therapeutic target in human ovarian cancer.
Coward J, Kulbe H, Chakravarty P, Leader D, Vassileva V, Leinster DA, Thompson R, Schioppa T, Nemeth J, Vermeulen J, Singh N, Avril N, Cummings J, Rexhepaj E, Jirström K, Gallagher WM, Brennan DJ, McNeish IA, Balkwill FR. Coward J, et al. Clin Cancer Res. 2011 Sep 15;17(18):6083-96. doi: 10.1158/1078-0432.CCR-11-0945. Epub 2011 Jul 27. Clin Cancer Res. 2011. PMID: 21795409 Free PMC article. Clinical Trial.
"Re-educating" tumor-associated macrophages by targeting NF-kappaB.
Hagemann T, Lawrence T, McNeish I, Charles KA, Kulbe H, Thompson RG, Robinson SC, Balkwill FR. Hagemann T, et al. Among authors: thompson rg. J Exp Med. 2008 Jun 9;205(6):1261-8. doi: 10.1084/jem.20080108. Epub 2008 May 19. J Exp Med. 2008. PMID: 18490490 Free PMC article.
A dynamic inflammatory cytokine network in the human ovarian cancer microenvironment.
Kulbe H, Chakravarty P, Leinster DA, Charles KA, Kwong J, Thompson RG, Coward JI, Schioppa T, Robinson SC, Gallagher WM, Galletta L; Australian Ovarian Cancer Study Group; Salako MA, Smyth JF, Hagemann T, Brennan DJ, Bowtell DD, Balkwill FR. Kulbe H, et al. Among authors: thompson rg. Cancer Res. 2012 Jan 1;72(1):66-75. doi: 10.1158/0008-5472.CAN-11-2178. Epub 2011 Nov 7. Cancer Res. 2012. PMID: 22065722 Free PMC article.
The peritoneal tumour microenvironment of high-grade serous ovarian cancer.
Leinster DA, Kulbe H, Everitt G, Thompson R, Perretti M, Gavins FN, Cooper D, Gould D, Ennis DP, Lockley M, McNeish IA, Nourshargh S, Balkwill FR. Leinster DA, et al. J Pathol. 2012 Jun;227(2):136-45. doi: 10.1002/path.4002. Epub 2012 Apr 18. J Pathol. 2012. PMID: 22322968 Free PMC article.
A CCR4 antagonist reverses the tumor-promoting microenvironment of renal cancer.
Berlato C, Khan MN, Schioppa T, Thompson R, Maniati E, Montfort A, Jangani M, Canosa M, Kulbe H, Hagemann UB, Duncan AR, Fletcher L, Wilkinson RW, Powles T, Quezada SA, Balkwill FR. Berlato C, et al. J Clin Invest. 2017 Mar 1;127(3):801-813. doi: 10.1172/JCI82976. Epub 2017 Jan 30. J Clin Invest. 2017. PMID: 28134623 Free PMC article.
237 results