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A randomized, double-blind, placebo-controlled trial to evaluate the efficacy, safety, tolerability, and pharmacokinetic/pharmacodynamic effects of a targeted exposure of intravenous repinotan in patients with acute ischemic stroke: modified Randomized Exposure Controlled Trial (mRECT).
Teal P, Davis S, Hacke W, Kaste M, Lyden PD; Modified Randomized Exposure Controlled Trial Study Investigators; Fierus M; Bayer HealthCare AG. Teal P, et al. Among authors: lyden pd. Stroke. 2009 Nov;40(11):3518-25. doi: 10.1161/STROKEAHA.109.551382. Epub 2009 Sep 10. Stroke. 2009. PMID: 19745176 Clinical Trial.
Safety and tolerability of NXY-059 for acute intracerebral hemorrhage: the CHANT Trial.
Lyden PD, Shuaib A, Lees KR, Davalos A, Davis SM, Diener HC, Grotta JC, Ashwood TJ, Hardemark HG, Svensson HH, Rodichok L, Wasiewski WW, Ahlberg G; CHANT Trial Investigators. Lyden PD, et al. Stroke. 2007 Aug;38(8):2262-9. doi: 10.1161/STROKEAHA.106.472746. Epub 2007 Jun 14. Stroke. 2007. PMID: 17569876 Clinical Trial.
Delayed detection of atrial fibrillation after ischemic stroke.
Kamel H, Lees KR, Lyden PD, Teal PA, Shuaib A, Ali M, Johnston SC; Virtual International Stroke Trials Archive Investigators. Kamel H, et al. Among authors: lyden pd. J Stroke Cerebrovasc Dis. 2009 Nov-Dec;18(6):453-7. doi: 10.1016/j.jstrokecerebrovasdis.2009.01.012. J Stroke Cerebrovasc Dis. 2009. PMID: 19900647
Phase IIB/III trial of tenecteplase in acute ischemic stroke: results of a prematurely terminated randomized clinical trial.
Haley EC Jr, Thompson JL, Grotta JC, Lyden PD, Hemmen TG, Brown DL, Fanale C, Libman R, Kwiatkowski TG, Llinas RH, Levine SR, Johnston KC, Buchsbaum R, Levy G, Levin B; Tenecteplase in Stroke Investigators. Haley EC Jr, et al. Among authors: lyden pd. Stroke. 2010 Apr;41(4):707-11. doi: 10.1161/STROKEAHA.109.572040. Epub 2010 Feb 25. Stroke. 2010. PMID: 20185783 Free PMC article. Clinical Trial.
Low body temperature does not compromise the treatment effect of alteplase.
Lees JS, Mishra NK, Saini M, Lyden PD, Shuaib A; Virtual International Stroke Trials Archive (VISTA) Collaborators. Lees JS, et al. Among authors: lyden pd. Stroke. 2011 Sep;42(9):2618-21. doi: 10.1161/STROKEAHA.110.611210. Epub 2011 Jul 14. Stroke. 2011. PMID: 21757664
242 results