Thomas RV - Search Results

1

The National Cancer Institute phase I study of 2',3'-dideoxyinosine administration in adults with AIDS or AIDS-related complex: analysis of activity and toxicity profiles.

Yarchoan R, Mitsuya H, Pluda JM, Marczyk KS, Thomas RV, Hartman NR, Brouwers P, Perno CF, Allain JP, Johns DG, et al. Yarchoan R, et al. Among authors: thomas rv. Rev Infect Dis. 1990 Jul-Aug;12 Suppl 5:S522-33. doi: 10.1093/clinids/12.supplement_5.s522. Rev Infect Dis. 1990. PMID: 1974724

2

Treatment of the acquired immunodeficiency syndrome (AIDS) and AIDS-related complex with a regimen of 3'-azido-2',3'-dideoxythymidine (azidothymidine or zidovudine) and acyclovir. A pilot study.

Surbone A, Yarchoan R, McAtee N, Blum MR, Maha M, Allain JP, Thomas RV, Mitsuya H, Lehrman SN, Leuther M, et al. Surbone A, et al. Among authors: thomas rv. Ann Intern Med. 1988 Apr;108(4):534-40. doi: 10.7326/0003-4819-108-4-534. Ann Intern Med. 1988. PMID: 2964805

3

Pharmacokinetics of 2',3'-dideoxyinosine in patients with severe human immunodeficiency infection. II. The effects of different oral formulations and the presence of other medications.

Hartman NR, Yarchoan R, Pluda JM, Thomas RV, Wyvill KM, Flora KP, Broder S, Johns DG. Hartman NR, et al. Among authors: thomas rv. Clin Pharmacol Ther. 1991 Sep;50(3):278-85. doi: 10.1038/clpt.1991.137. Clin Pharmacol Ther. 1991. PMID: 1914362

4

Long-term toxicity/activity profile of 2',3'-dideoxyinosine in AIDS or AIDS-related complex.

Yarchoan R, Pluda JM, Thomas RV, Mitsuya H, Brouwers P, Wyvill KM, Hartman N, Johns DG, Broder S. Yarchoan R, et al. Among authors: thomas rv. Lancet. 1990 Sep 1;336(8714):526-9. doi: 10.1016/0140-6736(90)92085-v. Lancet. 1990. PMID: 1975038

5

Initial clinical experience with dideoxynucleosides as single agents and in combination therapy.

Yarchoan R, Pluda JM, Perno CF, Mitsuya H, Thomas RV, Wyvill KM, Broder S. Yarchoan R, et al. Among authors: thomas rv. Ann N Y Acad Sci. 1990;616:328-43. doi: 10.1111/j.1749-6632.1990.tb17853.x. Ann N Y Acad Sci. 1990. PMID: 2078027 Review.

6

Pharmacokinetics of 2',3'-dideoxyadenosine and 2',3'-dideoxyinosine in patients with severe human immunodeficiency virus infection.

Hartman NR, Yarchoan R, Pluda JM, Thomas RV, Marczyk KS, Broder S, Johns DG. Hartman NR, et al. Among authors: thomas rv. Clin Pharmacol Ther. 1990 May;47(5):647-54. doi: 10.1038/clpt.1990.86. Clin Pharmacol Ther. 1990. PMID: 2111751 Clinical Trial.

7

Quantitative analysis of HIV-1 proviral DNA in peripheral blood mononuclear cells from patients with AIDS or ARC: decrease of proviral DNA content following treatment with 2',3'-dideoxyinosine (ddI).

Aoki S, Yarchoan R, Thomas RV, Pluda JM, Marczyk K, Broder S, Mitsuya H. Aoki S, et al. Among authors: thomas rv. AIDS Res Hum Retroviruses. 1990 Nov;6(11):1331-9. doi: 10.1089/aid.1990.6.1331. AIDS Res Hum Retroviruses. 1990. PMID: 2127682

8

In vivo activity against HIV and favorable toxicity profile of 2',3'-dideoxyinosine.

Yarchoan R, Mitsuya H, Thomas RV, Pluda JM, Hartman NR, Perno CF, Marczyk KS, Allain JP, Johns DG, Broder S. Yarchoan R, et al. Among authors: thomas rv. Science. 1989 Jul 28;245(4916):412-5. doi: 10.1126/science.2502840. Science. 1989. PMID: 2502840 Clinical Trial.

9

Phase I studies of 2',3'-dideoxycytidine in severe human immunodeficiency virus infection as a single agent and alternating with zidovudine (AZT).

Yarchoan R, Perno CF, Thomas RV, Klecker RW, Allain JP, Wills RJ, McAtee N, Fischl MA, Dubinsky R, McNeely MC, et al. Yarchoan R, et al. Among authors: thomas rv. Lancet. 1988 Jan 16;1(8577):76-81. doi: 10.1016/s0140-6736(88)90283-8. Lancet. 1988. PMID: 2891981

10

Pharmacokinetics of 2',3'-dideoxycytidine in patients with AIDS and related disorders.

Klecker RW Jr, Collins JM, Yarchoan RC, Thomas R, McAtee N, Broder S, Myers CE. Klecker RW Jr, et al. J Clin Pharmacol. 1988 Sep;28(9):837-42. doi: 10.1002/j.1552-4604.1988.tb03225.x. J Clin Pharmacol. 1988. PMID: 2852679

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