Sharrow SO - Search Results

1

Upregulation of CD4 expression during MHC class II-specific positive selection is essential for error-free lineage choice.

Sarafova SD, Van Laethem F, Adoro S, Guinter T, Sharrow SO, Feigenbaum L, Singer A. Sarafova SD, et al. Among authors: sharrow so. Immunity. 2009 Sep 18;31(3):480-90. doi: 10.1016/j.immuni.2009.07.006. Epub 2009 Sep 10. Immunity. 2009. PMID: 19747858 Free PMC article.

2

Coreceptor signal strength regulates positive selection but does not determine CD4/CD8 lineage choice in a physiologic in vivo model.

Erman B, Alag AS, Dahle O, van Laethem F, Sarafova SD, Guinter TI, Sharrow SO, Grinberg A, Love PE, Singer A. Erman B, et al. Among authors: sharrow so. J Immunol. 2006 Nov 15;177(10):6613-25. doi: 10.4049/jimmunol.177.10.6613. J Immunol. 2006. PMID: 17082573

3

Deletion of CD4 and CD8 coreceptors permits generation of alphabetaT cells that recognize antigens independently of the MHC.

Van Laethem F, Sarafova SD, Park JH, Tai X, Pobezinsky L, Guinter TI, Adoro S, Adams A, Sharrow SO, Feigenbaum L, Singer A. Van Laethem F, et al. Among authors: sharrow so. Immunity. 2007 Nov;27(5):735-50. doi: 10.1016/j.immuni.2007.10.007. Immunity. 2007. PMID: 18023370 Free article.

4

Lck availability during thymic selection determines the recognition specificity of the T cell repertoire.

Van Laethem F, Tikhonova AN, Pobezinsky LA, Tai X, Kimura MY, Le Saout C, Guinter TI, Adams A, Sharrow SO, Bernhardt G, Feigenbaum L, Singer A. Van Laethem F, et al. Among authors: sharrow so. Cell. 2013 Sep 12;154(6):1326-41. doi: 10.1016/j.cell.2013.08.009. Cell. 2013. PMID: 24034254 Free PMC article.

5

Unraveling a revealing paradox: Why major histocompatibility complex I-signaled thymocytes "paradoxically" appear as CD4+8lo transitional cells during positive selection of CD8+ T cells.

Bosselut R, Guinter TI, Sharrow SO, Singer A. Bosselut R, et al. Among authors: sharrow so. J Exp Med. 2003 Jun 16;197(12):1709-19. doi: 10.1084/jem.20030170. J Exp Med. 2003. PMID: 12810689 Free PMC article.

6

Modulation of coreceptor transcription during positive selection dictates lineage fate independently of TCR/coreceptor specificity.

Sarafova SD, Erman B, Yu Q, Van Laethem F, Guinter T, Sharrow SO, Feigenbaum L, Wildt KF, Ellmeier W, Singer A. Sarafova SD, et al. Among authors: sharrow so. Immunity. 2005 Jul;23(1):75-87. doi: 10.1016/j.immuni.2005.05.011. Immunity. 2005. PMID: 16039581 Free article.

7

Surface molecules that drive T cell development in vitro in the absence of thymic epithelium and in the absence of lineage-specific signals.

Cibotti R, Punt JA, Dash KS, Sharrow SO, Singer A. Cibotti R, et al. Among authors: sharrow so. Immunity. 1997 Mar;6(3):245-55. doi: 10.1016/s1074-7613(00)80327-1. Immunity. 1997. PMID: 9075925 Free article.

8

Positive selection as a developmental progression initiated by alpha beta TCR signals that fix TCR specificity prior to lineage commitment.

Bhandoola A, Cibotti R, Punt JA, Granger L, Adams AJ, Sharrow SO, Singer A. Bhandoola A, et al. Among authors: sharrow so. Immunity. 1999 Mar;10(3):301-11. doi: 10.1016/s1074-7613(00)80030-8. Immunity. 1999. PMID: 10204486 Free article.

9

Coreceptor reversal in the thymus: signaled CD4+8+ thymocytes initially terminate CD8 transcription even when differentiating into CD8+ T cells.

Brugnera E, Bhandoola A, Cibotti R, Yu Q, Guinter TI, Yamashita Y, Sharrow SO, Singer A. Brugnera E, et al. Among authors: sharrow so. Immunity. 2000 Jul;13(1):59-71. doi: 10.1016/s1074-7613(00)00008-x. Immunity. 2000. PMID: 10933395 Free article.

10

Strength of signaling by CD4 and CD8 coreceptor tails determines the number but not the lineage direction of positively selected thymocytes.

Bosselut R, Feigenbaum L, Sharrow SO, Singer A. Bosselut R, et al. Among authors: sharrow so. Immunity. 2001 Apr;14(4):483-94. doi: 10.1016/s1074-7613(01)00128-5. Immunity. 2001. PMID: 11336693 Free article.

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