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Fanconi anemia is associated with a defect in the BRCA2 partner PALB2.
Xia B, Dorsman JC, Ameziane N, de Vries Y, Rooimans MA, Sheng Q, Pals G, Errami A, Gluckman E, Llera J, Wang W, Livingston DM, Joenje H, de Winter JP. Xia B, et al. Nat Genet. 2007 Feb;39(2):159-61. doi: 10.1038/ng1942. Epub 2006 Dec 31. Nat Genet. 2007. PMID: 17200672
PALB2/FANCN: recombining cancer and Fanconi anemia.
Tischkowitz M, Xia B. Tischkowitz M, et al. Among authors: xia b. Cancer Res. 2010 Oct 1;70(19):7353-9. doi: 10.1158/0008-5472.CAN-10-1012. Epub 2010 Sep 21. Cancer Res. 2010. PMID: 20858716 Free PMC article. Review.
PALB2 interacts with KEAP1 to promote NRF2 nuclear accumulation and function.
Ma J, Cai H, Wu T, Sobhian B, Huo Y, Alcivar A, Mehta M, Cheung KL, Ganesan S, Kong AN, Zhang DD, Xia B. Ma J, et al. Among authors: xia b. Mol Cell Biol. 2012 Apr;32(8):1506-17. doi: 10.1128/MCB.06271-11. Epub 2012 Feb 13. Mol Cell Biol. 2012. PMID: 22331464 Free PMC article.
Coupling of Homologous Recombination and the Checkpoint by ATR.
Buisson R, Niraj J, Rodrigue A, Ho CK, Kreuzer J, Foo TK, Hardy EJ, Dellaire G, Haas W, Xia B, Masson JY, Zou L. Buisson R, et al. Among authors: xia b. Mol Cell. 2017 Jan 19;65(2):336-346. doi: 10.1016/j.molcel.2016.12.007. Epub 2017 Jan 12. Mol Cell. 2017. PMID: 28089683 Free PMC article.
Compromised BRCA1-PALB2 interaction is associated with breast cancer risk.
Foo TK, Tischkowitz M, Simhadri S, Boshari T, Zayed N, Burke KA, Berman SH, Blecua P, Riaz N, Huo Y, Ding YC, Neuhausen SL, Weigelt B, Reis-Filho JS, Foulkes WD, Xia B. Foo TK, et al. Among authors: xia b. Oncogene. 2017 Jul 20;36(29):4161-4170. doi: 10.1038/onc.2017.46. Epub 2017 Mar 20. Oncogene. 2017. PMID: 28319063 Free PMC article.
2,541 results