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Dengue virus specific IgY provides protection following lethal dengue virus challenge and is neutralizing in the absence of inducing antibody dependent enhancement.
Fink AL, Williams KL, Harris E, Alvine TD, Henderson T, Schiltz J, Nilles ML, Bradley DS. Fink AL, et al. Among authors: williams kl. PLoS Negl Trop Dis. 2017 Jul 7;11(7):e0005721. doi: 10.1371/journal.pntd.0005721. eCollection 2017 Jul. PLoS Negl Trop Dis. 2017. PMID: 28686617 Free PMC article.
The human immune response to Dengue virus is dominated by highly cross-reactive antibodies endowed with neutralizing and enhancing activity.
Beltramello M, Williams KL, Simmons CP, Macagno A, Simonelli L, Quyen NT, Sukupolvi-Petty S, Navarro-Sanchez E, Young PR, de Silva AM, Rey FA, Varani L, Whitehead SS, Diamond MS, Harris E, Lanzavecchia A, Sallusto F. Beltramello M, et al. Among authors: williams kl. Cell Host Microbe. 2010 Sep 16;8(3):271-83. doi: 10.1016/j.chom.2010.08.007. Cell Host Microbe. 2010. PMID: 20833378 Free PMC article.
547 results